Light up multiple protein dimers on cell surface based on proximity-induced fluorescence activation of DNA-templated sliver nanoclusters.

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第一作者： Lulu,Xu

第一单位： Molecular Medicine and Cancer Research Center, Chongqing Medical University, Chongqing, 400016, PR China; The Center for Clinical Molecular Medical Detection, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, PR China.

作者： Lulu,Xu ^[1] ; Zheng,Zhou ^[2] ; Xiaolong,Gou ^[3] ; Weicheng,Shi ^[3] ; Yao,Gong ^[3] ; Ming,Yi ^[3] ; Wei,Cheng ^[4] ; Fangzhou,Song ^[5]

作者单位： Molecular Medicine and Cancer Research Center, Chongqing Medical University, Chongqing, 400016, PR China; The Center for Clinical Molecular Medical Detection, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, PR China. ^[1] The Department of Clinical Laboratory, Chongqing University Three Gorges Hospital, Chongqing, 400016, PR China. ^[2] The Center for Clinical Molecular Medical Detection, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, PR China. ^[3] The Center for Clinical Molecular Medical Detection, The First Affiliated Hospital of Chongqing Medical University, Chongqing, 400016, PR China. Electronic address: chengwei@hospital.cqmu.edu.cn. ^[4] Molecular Medicine and Cancer Research Center, Chongqing Medical University, Chongqing, 400016, PR China. Electronic address: fzsongcq@163.com. ^[5]

关键词 Aptamer DNA-Templated sliver nanoclusters Fluorescent imaging Human epidermal growth factor receptor 2 Protein homodimer

主题词生物传感技术(Biosensing Techniques);DNA(DNA);人类(Humans);膜蛋白质类(Membrane Proteins);金属纳米粒子(Metal Nanoparticles);银(Silver);光谱法, 荧光(Spectrometry, Fluorescence)

DOI 10.1016/j.bios.2021.113064

PMID 33578114

发布时间 2021-05-14

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准确一般字义偏差语意偏离译文作用小提交