Intrahepatic cholangiocarcinoma: Morpho-molecular pathology, tumor reactive microenvironment, and malignant progression.

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作者： Alphonse E,Sirica ^[1] ; Mario,Strazzabosco ^[2] ; Massimiliano,Cadamuro ^[3]

作者单位： Department of Pathology, Virginia Commonwealth University School of Medicine, Richmond, VA, United States. Electronic address: alphonse.sirica@vcuhealth.org. ^[1] Liver Center and Section of Digestive Diseases, Department of Internal Medicine, Section of Digestive Diseases, Yale University School of Medicine, New Haven, CT, United States. ^[2] Department of Molecular Medicine, University of Padova, Padova, Italy. ^[3]

关键词 Cancer-associated fibroblasts Extracellular matrix Fibroinflammatory risk conditions Immune milieu M2 macrophages Morpho-molecular classification Periostin Therapeutic targeting Transforming growth factor-β Tumor reactive microenvironment

主题词动物(Animals);胆管肿瘤(Bile Duct Neoplasms);胆管上皮癌(Cholangiocarcinoma);疾病恶化(Disease Progression);人类(Humans);肿瘤微环境(Tumor Microenvironment)

DOI 10.1016/bs.acr.2020.10.005

PMID 33579427

发布时间 2023-11-05

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