Low dose of fire retardant, 2,2',4,4'-tetrabromodiphenyl ether (BDE47), stimulates the proliferation and differentiation of progenitor Leydig cells of male rats during prepuberty.

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作者： Zengqiang,Li ^[1] ; Huitao,Li ^[1] ; Changchang,Li ^[1] ; Haoni,Yan ^[1] ; Yingfen,Ying ^[2] ; Xiaoheng,Li ^[1] ; Qiqi,Zhu ^[2] ; Ren-Shan,Ge ^[3] ; Yiyan,Wang ^[4]

作者单位： Department of Anesthesiology, Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325027, China. ^[1] Department of Obstetrics and Gynecology, Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325027, China. ^[2] Department of Anesthesiology, Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325027, China; Department of Obstetrics and Gynecology, Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325027, China. Electronic address: r_ge@yahoo.com. ^[3] Department of Anesthesiology, Second Affiliated Hospital & Yuying Children's Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, 325027, China. Electronic address: wyy19880119@163.com. ^[4]

关键词 BDE47 Immature leydig cells Luteinizing hormone Proliferation p21 p53