Discovery of remogliflozin etabonate: A potent and highly selective SGLT2 inhibitor.

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第一作者： Kazuo,Shimizu

第一单位： Central Research Laboratory, Kissei Pharmaceutical Co., Ltd., 4365-1,Hotakakashiwabara, Azumino, Nagano 399-8304, Japan; Faculty of Pharmaceutical Sciences, Toho University, 2-2-1, Miyama, Funabashi, Chiba 274-8510, Japan. Electronic address: kazuo_shimizu@pharm.kissei.co.jp.

作者： Kazuo,Shimizu ^[1] ; Hideki,Fujikura ^[2] ; Nobuhiko,Fushimi ^[2] ; Toshihiro,Nishimura ^[2] ; Kazuya,Tatani ^[2] ; Kenji,Katsuno ^[2] ; Yoshikazu,Fujimori ^[2] ; Shinjiro,Watanabe ^[2] ; Masahiro,Hiratochi ^[2] ; Takeshi,Nakabayashi ^[2] ; Noboru,Kamada ^[2] ; Koichi,Arakawa ^[2] ; Hidemasa,Hikawa ^[3] ; Isao,Azumaya ^[4] ; Masayuki,Isaji ^[2]

作者单位： Central Research Laboratory, Kissei Pharmaceutical Co., Ltd., 4365-1,Hotakakashiwabara, Azumino, Nagano 399-8304, Japan; Faculty of Pharmaceutical Sciences, Toho University, 2-2-1, Miyama, Funabashi, Chiba 274-8510, Japan. Electronic address: kazuo_shimizu@pharm.kissei.co.jp. ^[1] Central Research Laboratory, Kissei Pharmaceutical Co., Ltd., 4365-1,Hotakakashiwabara, Azumino, Nagano 399-8304, Japan. ^[2] Faculty of Pharmaceutical Sciences, Toho University, 2-2-1, Miyama, Funabashi, Chiba 274-8510, Japan. ^[3] Faculty of Pharmaceutical Sciences, Toho University, 2-2-1, Miyama, Funabashi, Chiba 274-8510, Japan. Electronic address: isao.azumaya@phar.toho-u.ac.jp. ^[4]

关键词 O-glucoside Remogliflozin etabonate SGLT2 inhibitor Type 2 diabetes mellitus