Integrated molecular analysis of adult sonic hedgehog (SHH)-activated medulloblastomas reveals two clinically relevant tumor subsets with VEGFA as potent prognostic indicator.

导出 LinkOut

翻译打印收藏纠错

作者： Andrey,Korshunov ^[1] ; Konstantin,Okonechnikov ^[2] ; Damian,Stichel ^[3] ; Marina,Ryzhova ^[3] ; Daniel,Schrimpf ^[4] ; Felix,Sahm ^[1] ; Philipp,Sievers ^[2] ; Oksana,Absalyamova ^[5] ; Olga,Zheludkova ^[1] ; Andrey,Golanov ^[2] ; David T W,Jones ^[1] ; Stefan M,Pfister ^[2] ; Andreas,von Deimling ^[3] ; Marcel,Kool ^[1]

作者单位： Clinical Cooperation Unit Neuropathology (B300), German Cancer Research Center (DKFZ), Heidelberg, Germany. ^[1] Department of Neuropathology, University of Heidelberg, Heidelberg, Germany. ^[2] Hopp Children's Cancer Center Heidelberg (KiTZ), Heidelberg, Germany. ^[3] Division of Pediatric Neuro-oncology, German Cancer Consortium (DKTK) and German Cancer Research Center (DKFZ), Heidelberg, Germany. ^[4] N.N. Burdenko Neurosurgical Research Centre, Moscow, Russia. ^[5] Department of Neuro-Oncology, Russian Scientific Center of Radiology, Moscow, Russia. ^[6] Pediatric Glioma Research Group (B360), German Cancer Research Center (DKFZ), Heidelberg, Germany. ^[7] Department of Pediatric Oncology, Hematology & Immunology, University of Heidelberg, Heidelberg, Germany. ^[8] Princess Máxima Center for Pediatric Oncology, Utrecht, the Netherlands. ^[9]

关键词 SHH VEGFA adult medulloblastoma prognosis transcriptome