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A zebrafish forward genetic screen identifies an indispensable threonine residue in the kinase domain of PRKD2.

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第一作者： Panagiota,Giardoglou

第一单位： Zebrafish Disease Model lab, Biomedical Research Foundation Academy of Athens, Athens 115 27, Greece.;Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University of Athens, Athens 176 71, Greece.

作者： Panagiota,Giardoglou ^[1] ; Despina,Bournele ^[2] ; Misun,Park ^[3] ; Stavroula,Kanoni ^[4] ; George V,Dedoussis ^[5] ; Susan F,Steinberg ^[3] ; Panos,Deloukas ^[6] ; Dimitris,Beis ^[7]

作者单位： Zebrafish Disease Model lab, Biomedical Research Foundation Academy of Athens, Athens 115 27, Greece.;Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University of Athens, Athens 176 71, Greece. ^[1] Zebrafish Disease Model lab, Biomedical Research Foundation Academy of Athens, Athens 115 27, Greece. ^[2] Department of Pharmacology, Columbia University, New York 100 27, USA. ^[3] William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Clinical Pharmacology Centre, Queen Mary University of London, London, EC1M 6BQ, UK. ^[4] Department of Nutrition and Dietetics, School of Health Science and Education, Harokopio University of Athens, Athens 176 71, Greece. ^[5] William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Clinical Pharmacology Centre, Queen Mary University of London, London, EC1M 6BQ, UK.;Princess Al-Jawhara Al-Brahim Centre of Excellence in Research of Hereditary Disorders (PACER-HD), King Abdulaziz University, Jeddah 222 52, Saudi Arabia. ^[6] Zebrafish Disease Model lab, Biomedical Research Foundation Academy of Athens, Athens 115 27, Greece dbeis@bioacademy.gr. ^[7]

关键词 Cardiac valves Cardiovascular development Protein kinase D2 Zebrafish