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Stringent thresholds in SARS-CoV-2 IgG assays lead to under-detection of mild infections.

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第一作者： David W,Eyre

第一单位： Big Data Institute, Nuffield Department of Population Health, University of Oxford, Oxford, UK. david.eyre@bdi.ox.ac.uk.;Oxford University Hospitals NHS Foundation Trust, Oxford, UK. david.eyre@bdi.ox.ac.uk.;NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK. david.eyre@bdi.ox.ac.uk.;NIHR Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance at University of Oxford in partnership with Public Health England, Oxford, UK. david.eyre@bdi.ox.ac.uk.;Microbiology Department, John Radcliffe Hospital, Headley Way, Oxford, OX3 9DU, UK. david.eyre@bdi.ox.ac.uk.

作者： David W,Eyre ^[1] ; Sheila F,Lumley ^[2] ; Denise,O'Donnell ^[3] ; Nicole E,Stoesser ^[4] ; Philippa C,Matthews ^[5] ; Alison,Howarth ^[3] ; Stephanie B,Hatch ^[3] ; Brian D,Marsden ^[6] ; Stuart,Cox ^[7] ; Tim,James ^[7] ; Richard J,Cornall ^[3] ; David I,Stuart ^[3] ; Gavin,Screaton ^[3] ; Daniel,Ebner ^[8] ; Derrick W,Crook ^[5] ; Christopher P,Conlon ^[2] ; Katie,Jeffery ^[7] ; Timothy M,Walker ^[9] ; Timothy E A,Peto ^[5]

作者单位： Big Data Institute, Nuffield Department of Population Health, University of Oxford, Oxford, UK. david.eyre@bdi.ox.ac.uk.;Oxford University Hospitals NHS Foundation Trust, Oxford, UK. david.eyre@bdi.ox.ac.uk.;NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK. david.eyre@bdi.ox.ac.uk.;NIHR Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance at University of Oxford in partnership with Public Health England, Oxford, UK. david.eyre@bdi.ox.ac.uk.;Microbiology Department, John Radcliffe Hospital, Headley Way, Oxford, OX3 9DU, UK. david.eyre@bdi.ox.ac.uk. ^[1] Oxford University Hospitals NHS Foundation Trust, Oxford, UK.;Nuffield Department of Medicine, University of Oxford, Oxford, UK. ^[2] Nuffield Department of Medicine, University of Oxford, Oxford, UK. ^[3] Oxford University Hospitals NHS Foundation Trust, Oxford, UK.;NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK.;NIHR Health Protection Research Unit in Healthcare Associated Infections and Antimicrobial Resistance at University of Oxford in partnership with Public Health England, Oxford, UK.;Nuffield Department of Medicine, University of Oxford, Oxford, UK. ^[4] Oxford University Hospitals NHS Foundation Trust, Oxford, UK.;NIHR Oxford Biomedical Research Centre, University of Oxford, Oxford, UK.;Nuffield Department of Medicine, University of Oxford, Oxford, UK. ^[5] Nuffield Department of Medicine, University of Oxford, Oxford, UK.;Kennedy Institute of Rheumatology Research, University of Oxford, Oxford, UK. ^[6] Oxford University Hospitals NHS Foundation Trust, Oxford, UK. ^[7] Nuffield Department of Medicine, University of Oxford, Oxford, UK.;Target Discovery Institute, University of Oxford, Oxford, UK. ^[8] Oxford University Hospitals NHS Foundation Trust, Oxford, UK.;Nuffield Department of Medicine, University of Oxford, Oxford, UK.;Oxford University Clinical Research Unit, Ho Chi Minh City, Vietnam. ^[9]

关键词 Ageusia Anosmia Antibodies COVID-19 SARS-CoV-2 Serology