TGR5 controls bile acid composition and gallbladder function to protect the liver from bile acid overload.
第一单位:
Université Paris Saclay, Faculté des Sciences d'Orsay, INSERM U.1193, bât. 443, 91405, Orsay, France.
作者:
关键词
ALP, alkaline phosphataseALT, alanine aminotransferaseBA, bile acidBDL, bile duct ligationBile acidsCA, cholic acidCC, cholecystectomyCT, cholestyramineCYP, cytochrome P450EH, extended hepatectomyGB, gallbladderGM, gut microbiotaGPBAR1GPBAR1, G protein-coupled bile acid receptor 1GallbladderHI, hydrophobicity indexHepatoprotectionKO, knockoutND, normal dietOA, oleanolic acidPH, partial hepatectomyTBA, total BATGR5TGR5, Takeda G protein coupled receptorUDCA, ursodeoxycholic acidWT, wild-type
DOI
10.1016/j.jhepr.2020.100214
PMID
33604531
发布时间
2022-04-20
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JHEP reports
2021年3卷2期
100214页
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