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Disruption of brainstem monoaminergic fibre tracts in multiple sclerosis as a putative mechanism for cognitive fatigue: a fixel-based analysis.

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第一作者： Tiziana,Carandini

第一单位： Department of Neuroscience, Brighton and Sussex Medical School, University of Sussex, UK; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy. Electronic address: tiziana.carandini@policlinico.mi.it.

作者： Tiziana,Carandini ^[1] ; Matteo,Mancini ^[2] ; Iulia,Bogdan ^[3] ; Charlotte L,Rae ^[4] ; Andrew W,Barritt ^[3] ; Arjun,Sethi ^[5] ; Neil,Harrison ^[6] ; Waqar,Rashid ^[3] ; Elio,Scarpini ^[7] ; Daniela,Galimberti ^[7] ; Marco,Bozzali ^[8] ; Mara,Cercignani ^[9]

作者单位： Department of Neuroscience, Brighton and Sussex Medical School, University of Sussex, UK; Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy. Electronic address: tiziana.carandini@policlinico.mi.it. ^[1] Department of Neuroscience, Brighton and Sussex Medical School, University of Sussex, UK; NeuroPoly Lab, Polytechnique Montreal, Montreal, Canada; CUBRIC, Cardiff University, Cardiff, UK. ^[2] Department of Neuroscience, Brighton and Sussex Medical School, University of Sussex, UK. ^[3] School of Psychology, University of Sussex, UK. ^[4] Psychiatry, Psychology & Neuroscience, King's College, London, UK. ^[5] Department of Psychology and Department of Medicine, Cardiff, UK. ^[6] Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy; Department of Biomedical, Surgical and Dental Sciences, University of Milan, Dino Ferrari Center, Milan, Italy. ^[7] Department of Neuroscience, Brighton and Sussex Medical School, University of Sussex, UK; Rita Levi Montalcini Department of Neuroscience, University of Torino, Turin, Italy. ^[8] Department of Neuroscience, Brighton and Sussex Medical School, University of Sussex, UK; Neuroimaging Laboratory, Santa Lucia Foundation IRCCS, Rome, Italy. ^[9]

关键词 Fatigue Fixel-based analysis Monoaminergic system Multiple sclerosis Tractography

医学主题词脑干(Brain Stem);认知(Cognition);弥散张量成像(Diffusion Tensor Imaging);人类(Humans);多发性硬化(Multiple Sclerosis)

DOI 10.1016/j.nicl.2021.102587

PMID 33610097

发布时间 2021-07-30

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