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Adoptive T cell immunotherapy for medullary thyroid carcinoma targeting GDNF family receptor alpha 4.

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第一作者： Vijay G,Bhoj

第一单位： Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.;Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.

作者： Vijay G,Bhoj ^[1] ; Lucy,Li ^[1] ; Kalpana,Parvathaneni ^[1] ; Zheng,Zhang ^[1] ; Stephen,Kacir ^[2] ; Dimitrios,Arhontoulis ^[1] ; Kenneth,Zhou ^[1] ; Bevin,McGettigan-Croce ^[1] ; Selene,Nunez-Cruz ^[1] ; Gayathri,Gulendran ^[1] ; Alina C,Boesteanu ^[3] ; Laura,Johnson ^[3] ; Michael D,Feldman ^[2] ; Enrico,Radaelli ^[4] ; Keith,Mansfield ^[5] ; MacLean,Nasrallah ^[2] ; Rebecca S,Goydel ^[6] ; Haiyong,Peng ^[6] ; Christoph,Rader ^[6] ; Michael C,Milone ^[1] ; Don L,Siegel ^[1]

作者单位： Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.;Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. ^[1] Department of Pathology and Laboratory Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. ^[2] Center for Cellular Immunotherapies, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. ^[3] Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA. ^[4] Discovery and Investigative Pathology, Novartis Institute for Biomedical Research, Cambridge, MA 02139, USA. ^[5] Department of Immunology and Microbiology, The Scripps Research Institute, Jupiter, FL 33458, USA. ^[6]

关键词 CAR T cells GFRa4 Medullary thyroid carcinoma RETMC immunotherapy

DOI 10.1016/j.omto.2021.01.012

PMID 33614919

发布时间 2022-05-24

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Molecular therapy oncolytics

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Adoptive T cell immunotherapy for medullary thyroid carcinoma targeting GDNF family receptor alpha 4.

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