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Therapeutic Assessment of Targeting ASNS Combined with l-Asparaginase Treatment in Solid Tumors and Investigation of Resistance Mechanisms.

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第一作者： Verena,Apfel

第一单位： Disease area Oncology, Novartis Institute for Biomedical Research, Basel, Switzerland.

作者： Verena,Apfel ^[1] ; Damien,Begue ^[2] ; Valentina,Cordo' ^[1] ; Laura,Holzer ^[1] ; Laetitia,Martinuzzi ^[1] ; Alexandra,Buhles ^[1] ; Grainne,Kerr ^[1] ; Ines,Barbosa ^[1] ; Ulrike,Naumann ^[2] ; Michelle,Piquet ^[3] ; David,Ruddy ^[3] ; Andreas,Weiss ^[1] ; Stephane,Ferretti ^[1] ; Reinaldo,Almeida ^[4] ; Debora,Bonenfant ^[2] ; Luca,Tordella ^[1] ; Giorgio G,Galli ^[1]

作者单位： Disease area Oncology, Novartis Institute for Biomedical Research, Basel, Switzerland. ^[1] Analytical Sciences and Imaging, Novartis Institutes for Biomedical Research, CH-4002 Basel, Switzerland. ^[2] Disease area Oncology, Novartis Institute for Biomedical Research, Cambridge, Massachusetts 02139United States. ^[3] Global Discovery Chemistry, Novartis Institutes for Biomedical Research, CH-4002 Basel, Switzerland. ^[4]

DOI 10.1021/acsptsci.0c00196

PMID 33615182

发布时间 2022-01-14

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ACS pharmacology & translational science

2021年4卷1期

327-337页

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Therapeutic Assessment of Targeting ASNS Combined with l-Asparaginase Treatment in Solid Tumors and Investigation of Resistance Mechanisms.

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Therapeutic Assessment of Targeting ASNS Combined with l-Asparaginase Treatment in Solid Tumors and Investigation of Resistance Mechanisms.

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