Pseudo Natural Products-Chemical Evolution of Natural Product Structure.

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作者： George,Karageorgis ^[1] ; Daniel J,Foley ^[2] ; Luca,Laraia ^[3] ; Susanne,Brakmann ^[4] ; Herbert,Waldmann ^[5]

作者单位： Max-Planck Institute of Molecular Physiology, Otto-Hahn Strasse 11, 44227, Dortmund, Germany. ^[1] Max-Planck Institute of Molecular Physiology, Otto-Hahn Strasse 11, 44227, Dortmund, Germany.;Current address: School of Physical and Chemical Sciences, University of Canterbury, Private Bag 4800, Christchurch, 8140, New Zealand. ^[2] Max-Planck Institute of Molecular Physiology, Otto-Hahn Strasse 11, 44227, Dortmund, Germany.;Current address: Department of Chemistry, Technical University of Denmark, kemitorvet 207, 2800 Kgs., Lyngby, Denmark. ^[3] Faculty of Chemistry and Chemical Biology, TU Dortmund University, Otto-Hahn Strasse 4a, 44227, Dortmund, Germany. ^[4] Max-Planck Institute of Molecular Physiology, Otto-Hahn Strasse 11, 44227, Dortmund, Germany.;Faculty of Chemistry and Chemical Biology, TU Dortmund University, Otto-Hahn Strasse 4a, 44227, Dortmund, Germany. ^[5]

关键词 biological activity chemical biology fragment-based design natural products natural selection

DOI 10.1002/anie.202016575

PMID 33644925

发布时间 2024-07-24

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