Low risk of the TMPRSS2 inhibitor camostat mesylate and its metabolite GBPA to act as perpetrators of drug-drug interactions.
第一作者:
Johanna,Weiss
第一单位:
Department of Clinical Pharmacology and Pharmacoepidemiology, University of Heidelberg, Im Neuenheimer Feld 410, 69120, Heidelberg, Germany. Electronic address: johanna.weiss@med.uni-heidelberg.de.
作者:
医学主题词
细胞系(Cell Line);细胞存活(Cell Survival);细胞色素P450 CYP1A1(Cytochrome P-450 CYP1A1);细胞色素P-450 CYP3A(Cytochrome P-450 CYP3A);药物相互作用(Drug Interactions);酯类(Esters);胍类(Guanidines);人类(Humans);有机阴离子转运子(Organic Anion Transporters);RNA, 信使(RNA, Messenger);受体, 芳基烃(Receptors, Aryl Hydrocarbon);丝氨酸内肽酶类(Serine Endopeptidases);丝氨酸蛋白酶抑制剂(Serine Proteinase Inhibitors)
DOI
10.1016/j.cbi.2021.109428
PMID
33647240
发布时间
2024-09-09
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