Single nucleotide variants in immune-response genes and the tumor microenvironment composition predict progression of mantle cell lymphoma.

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作者： Guilherme Rossi,Assis-Mendonça ^[1] ; André,Fattori ^[2] ; Rafael Malagoli,Rocha ^[3] ; Gustavo Jacob,Lourenço ^[4] ; Márcia Torresan,Delamain ^[5] ; Suely,Nonogaki ^[6] ; Vladmir Cláudio Cordeiro,de Lima ^[7] ; Gisele Wally Braga,Colleoni ^[8] ; Cármino Antonio,de Souza ^[2] ; Fernando Augusto,Soares ^[5] ; Carmen Silvia Passos,Lima ^[9] ; José,Vassallo ^[2]

作者单位： Department of Pathology, Faculty of Medical Sciences, University of Campinas, Distrito de Barão Geraldo, Campinas, SP, Brazil. guilhermeram13@yahoo.com.br. ^[1] Department of Internal Medicine, Faculty of Medical Sciences, University of Campinas, Campinas, SP, Brazil. ^[2] Molecular Gynecology Laboratory, Department of Gynecology, Federal University of São Paulo, São Paulo, Brazil. ^[3] Laboratory of Cancer Genetics, Faculty of Medical Sciences, University of Campinas, Campinas, SP, Brazil. ^[4] Hematology and Hemotherapy Center, University of Campinas, Campinas, Brazil. ^[5] Instituto Adolfo Lutz, Secretaria de Estado da Saúde, São Paulo, SP, Brazil. ^[6] Department of Medical Oncology, A C Camargo Cancer Center, São Paulo, Brazil. ^[7] Department of Clinical and Experimental Oncology, Federal University of São Paulo, São Paulo, SP, Brazil. ^[8] Rede D'Or Hospitals Network - Pathology Division, São Paulo, SP, Brazil. ^[9] Department of Pathology, Faculty of Medical Sciences, University of Campinas, Distrito de Barão Geraldo, Campinas, SP, Brazil. ^[10] Laboratory of Investigative and Molecular Pathology (LIP), CIPED, Faculty of Medical Sciences, University of Campinas, Campinas, SP, Brazil. ^[11]

关键词 Immunohistochemistry Mantle cell lymphoma Prognostic factors SNVs Tumor microenvironment