换一批HMGA1-TRIP13 axis promotes stemness and epithelial mesenchymal transition of perihilar cholangiocarcinoma in a positive feedback loop dependent on c-Myc.
第一作者：
Zhipeng,Li
第一单位：
Department of General Surgery, Qilu Hospital, Cheeloo College of Medicine, Shandong University, 107 Wenhuaxi Road, Jinan, 250012, Shandong, China.;Department of General Surgery, Shandong Second Provincial General Hospital, Shandong Provincial ENT Hospital, Jinan, China.
作者：
医学主题词
动物(Animals);胆管肿瘤(Bile Duct Neoplasms);细胞周期蛋白质类(Cell Cycle Proteins);胆管上皮癌(Cholangiocarcinoma);疾病恶化(Disease Progression);上皮-间质转化(Epithelial-Mesenchymal Transition);反馈, 生理(Feedback, Physiological);女(雌)性(Female);HMGA1a蛋白(HMGA1a Protein);人类(Humans);小鼠(Mice);小鼠, 裸(Mice, Nude);预后(Prognosis);原癌基因蛋白质c-myc(Proto-Oncogene Proteins c-myc);回顾性研究(Retrospective Studies);信号传导(Signal Transduction);转染(Transfection)
DOI
10.1186/s13046-021-01890-1
PMID
33648560
发布时间
2025-09-16
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