<i>Fusobacterium nucleatum</i> Secretes Outer Membrane Vesicles and Promotes Intestinal Inflammation.

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作者： Melinda A,Engevik ^[1] ; Heather A,Danhof ^[2] ; Wenly,Ruan ^[3] ; Amy C,Engevik ^[4] ; Alexandra L,Chang-Graham ^[5] ; Kristen A,Engevik ^[3] ; Zhongcheng,Shi ^[3] ; Yanling,Zhao ^[6] ; Colleen K,Brand ^[2] ; Evan S,Krystofiak ^[7] ; Susan,Venable ^[3] ; Xinli,Liu ^[8] ; Kendal D,Hirschi ^[6] ; Joseph M,Hyser ^[2] ; Jennifer K,Spinler ^[9] ; Robert A,Britton ^[10] ; James,Versalovic ^[3]

作者单位： Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas, USA melinda.engevik@bcm.edu. ^[1] Department of Pathology, Texas Children's Hospital, Houston, Texas, USA. ^[2] Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, Texas, USA. ^[3] Department of Pediatrics, Baylor College of Medicine, Houston, Texas, USA. ^[4] Department of Surgical Sciences, Vanderbilt University Medical Center, Nashville Tennessee, USA. ^[5] Department of Pathology and Immunology, Baylor College of Medicine, Houston, Texas, USA. ^[6] Department of Pediatrics, Texas Children's Cancer Center, Texas Children's Hospital, Houston, Texas, USA. ^[7] Department of Cell and Developmental Biology, Vanderbilt University, Nashville, Tennessee, USA. ^[8] Department of Pharmacological and Pharmaceutical Sciences, University of Houston, Houston, Texas, USA. ^[9] Department of Pediatrics and Human and Molecular Genetics, Children's Nutrition Research Center, Baylor College of Medicine, Houston, Texas, USA. ^[10]

关键词 Fusobacterium nucleatum TLR4 enteroids epithelium inflammation intestine microbiome organoids outer membrane vesicles