Type 1 diabetic Akita mice have low bone mass and impaired fracture healing.

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作者： Pei,Hu ^[1] ; Jennifer A,McKenzie ^[2] ; Evan G,Buettmann ^[3] ; Nicole,Migotsky ^[3] ; Michael J,Gardner ^[4] ; Matthew J,Silva ^[5]

作者单位： State Key Laboratory of Oral Diseases, West China School of Stomatology, Sichuan University, Chengdu 610041, Sichuan, China; Department of Orthopaedic Surgery and Musculoskeletal Research Center, Washington University School of Medicine, Saint Louis, MO, United States. ^[1] Department of Orthopaedic Surgery and Musculoskeletal Research Center, Washington University School of Medicine, Saint Louis, MO, United States. ^[2] Department of Orthopaedic Surgery and Musculoskeletal Research Center, Washington University School of Medicine, Saint Louis, MO, United States; Department of Biomedical Engineering, Washington University, Saint Louis, MO, United States. ^[3] Department of Orthopaedic Surgery, Stanford University School of Medicine, Stanford, CA, United States. ^[4] Department of Orthopaedic Surgery and Musculoskeletal Research Center, Washington University School of Medicine, Saint Louis, MO, United States; Department of Biomedical Engineering, Washington University, Saint Louis, MO, United States. Electronic address: silvam@wustl.edu. ^[5]

关键词 Akita diabetic mouse Bone formation Bone strength Cartilage Fracture healing

主题词动物(Animals);骨痂(Bony Callus);糖尿病, 1型(Diabetes Mellitus, Type 1);股骨骨折(Femoral Fractures);股骨(Femur);骨折愈合(Fracture Healing);小鼠(Mice)

DOI 10.1016/j.bone.2021.115906

PMID 33662611

发布时间 2024-09-23

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