Prognostic value of the micronucleus assay for clinical endpoints in neoadjuvant radiochemotherapy for rectal cancer.

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作者： Leif Hendrik,Dröge ^[1] ; Steffen,Hennies ^[2] ; Stephan,Lorenzen ^[3] ; Lena-Christin,Conradi ^[4] ; Henriette,Quack ^[5] ; Torsten,Liersch ^[6] ; Christian,Helms ^[7] ; Miriam Alice,Frank ^[6] ; Markus Anton,Schirmer ^[8] ; Margret,Rave-Fränk ^[8] ; Tim,Beißbarth ^[8] ; Hendrik Andreas,Wolff ^[8]

作者单位： Department of Radiotherapy and Radiation Oncology, University Medical Center Göttingen, Robert-Koch-Str. 40, 37075, Göttingen, Germany. hendrik.droege@med.uni-goettingen.de. ^[1] University Medical Center Göttingen, Göttingen, Germany. ^[2] Department of Radiology, Nuclear Medicine and Radiotherapy, Radiology Munich, 80333, Munich, Germany. ^[3] Institute of Medical Bioinformatics, University Medical Center Göttingen, Göttingen, Germany. ^[4] Department of Molecular Medicine, Bernhard Nocht Institute for Tropical Medicine, Hamburg, Germany. ^[5] Department of General, Visceral and Pediatric Surgery, University Medical Center Göttingen, Göttingen, Germany. ^[6] Department of Hematology and Medical Oncology, University Medical Center Göttingen, Göttingen, Germany. ^[7] Department of Radiotherapy and Radiation Oncology, University Medical Center Göttingen, Robert-Koch-Str. 40, 37075, Göttingen, Germany. ^[8] Department of Radiotherapy and Radiation Oncology, University Medical Center Regensburg, Regensburg, Germany. ^[9]

关键词 Cytogenetic damage Micronucleus test Radiochemotherapy Rectal cancer Survival Toxicity