Long-Read Sequencing Improves the Detection of Structural Variations Impacting Complex Non-Coding Elements of the Genome.

导出 OA

翻译打印收藏纠错

作者： Ghausia,Begum ^[1] ; Ammar,Albanna ^[1] ; Asma,Bankapur ^[2] ; Nasna,Nassir ^[1] ; Richa,Tambi ^[1] ; Bakhrom K,Berdiev ^[1] ; Hosneara,Akter ^[1] ; Noushad,Karuvantevida ^[3] ; Barbara,Kellam ^[4] ; Deena,Alhashmi ^[1] ; Wilson W L,Sung ^[5] ; Bhooma,Thiruvahindrapuram ^[6] ; Alawi,Alsheikh-Ali ^[1] ; Stephen W,Scherer ^[6] ; Mohammed,Uddin ^[6]

作者单位： College of Medicine, Mohammed Bin Rashid University of Medicine and Health Sciences, Dubai 505055, United Arab Emirates. ^[1] Department of Psychiatry, Al Jalila Children's Specialty Hospital, Dubai 7662, United Arab Emirates. ^[2] Genetics and Genomic Medicine Centre, NeuroGen Children's Healthcare, Dhaka 1205, Bangladesh. ^[3] Department of Biochemistry and Molecular Biology, Dhaka University, Dhaka 1000, Bangladesh. ^[4] Department of Biotechnology, Bharathidasan University, Tiruchirappalli 620024, India. ^[5] The Centre for Applied Genomics, The Hospital for Sick Children, Toronto, ON M5S 1A1, Canada. ^[6] Department of Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada. ^[7] McLaughlin Centre and Department of Molecular Genetics, University of Toronto, Toronto, ON M5S, Canada. ^[8]

关键词 Oxford Nanopore Technology (ONT)long-read sequencing non-coding RNA structural variation whole-genome sequencing (WGS)