IFN signaling and neutrophil degranulation transcriptional signatures are induced during SARS-CoV-2 infection.

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第一作者： Bruce A,Rosa

第一单位： Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA.

作者： Bruce A,Rosa ^[1] ; Mushtaq,Ahmed ^[2] ; Dhiraj K,Singh ^[3] ; José Alberto,Choreño-Parra ^[4] ; Journey,Cole ^[3] ; Luis Armando,Jiménez-Álvarez ^[4] ; Tatiana Sofía,Rodríguez-Reyna ^[5] ; Bindu,Singh ^[3] ; Olga,Gonzalez ^[3] ; Ricardo,Carrion ^[3] ; Larry S,Schlesinger ^[3] ; John,Martin ^[1] ; Joaquín,Zúñiga ^[4] ; Makedonka,Mitreva ^[6] ; Deepak,Kaushal ^[7] ; Shabaana A,Khader ^[8]

作者单位： Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA. ^[1] Department of Molecular Microbiology, Washington University in St. Louis, St. Louis, MO, USA. ^[2] Southwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, TX, USA. ^[3] Laboratory of Immunobiology and Genetics, Instituto Nacional de Enfermedades Respiratorias Ismael Cosío Villegas, Mexico City, Mexico. ^[4] Department of Immunology and Rheumatology, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Mexico City, Mexico. ^[5] Department of Medicine, Washington University in St. Louis, St. Louis, MO, USA. mmitreva@wustl.edu. ^[6] Southwest National Primate Research Center, Texas Biomedical Research Institute, San Antonio, TX, USA. dkaushal@txbiomed.org. ^[7] Department of Molecular Microbiology, Washington University in St. Louis, St. Louis, MO, USA. sakhader@wustl.edu. ^[8]

主题词老年人(Aged);动物(Animals);细胞脱颗粒(Cell Degranulation);胶原(Collagen);疾病模型, 动物(Disease Models, Animal);女(雌)性(Female);基因表达调控(Gene Expression Regulation);人类(Humans);干扰素类(Interferons);肺(Lung);猕猴(Macaca mulatta);男(雄)性(Male);中年人(Middle Aged);中性白细胞(Neutrophils);受体, Notch(Receptors, Notch);信号传导(Signal Transduction);转化生长因子β(Transforming Growth Factor beta);血管内皮生长因子A(Vascular Endothelial Growth Factor A)

DOI 10.1038/s42003-021-01829-4

PMID 33674719

发布时间 2024-01-31

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Communications biology

2021年4卷1期

290页

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IFN signaling and neutrophil degranulation transcriptional signatures are induced during SARS-CoV-2 infection.

Communications biology

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IFN signaling and neutrophil degranulation transcriptional signatures are induced during SARS-CoV-2 infection.

Communications biology

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Communications biology

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