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A long isoform of GIV/Girdin contains a PDZ-binding module that regulates localization and G-protein binding.

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第一作者： Jason,Ear

第一单位： Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, California, USA; Biological Sciences Department, California State Polytechnic University, Pomona, California, USA. Electronic address: jear@cpp.edu.

作者： Jason,Ear ^[1] ; Amer Ali,Abd El-Hafeez ^[2] ; Suchismita,Roy ^[3] ; Tony,Ngo ^[3] ; Navin,Rajapakse ^[4] ; Julie,Choi ^[4] ; Soni,Khandelwal ^[5] ; Majid,Ghassemian ^[6] ; Luke,McCaffrey ^[7] ; Irina,Kufareva ^[3] ; Debashis,Sahoo ^[5] ; Pradipta,Ghosh ^[8]

作者单位： Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, California, USA; Biological Sciences Department, California State Polytechnic University, Pomona, California, USA. Electronic address: jear@cpp.edu. ^[1] Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, California, USA; Pharmacology and Experimental Oncology Unit, Cancer Biology Department, National Cancer Institute, Cairo University, Cairo, Egypt. ^[2] Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California San Diego, La Jolla, California, USA. ^[3] Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, California, USA. ^[4] Department of Pediatrics, University of California San Diego, La Jolla, California, USA. ^[5] Department of Chemistry and Biochemistry, University of California San Diego, La Jolla, California, USA. ^[6] Rosalind and Morris Goodman Cancer Research Centre, McGill University, Montreal, Canada; Gerald Bronfman Department of Oncology, McGill University, Montreal, Canada. ^[7] Department of Cellular and Molecular Medicine, University of California San Diego, La Jolla, California, USA; Department of Medicine, University of California San Diego, La Jolla, California, USA; Rebecca and John Moore Comprehensive Cancer Center, University of California San Diego, La Jolla, California, USA; Veterans Affairs Medical Center, La Jolla, California, USA. Electronic address: prghosh@ucsd.edu. ^[8]

关键词 cancer cell biology cell junctions cell signaling protein interactions