An efficient system for intestinal on-site butyrate production using novel microbiome-derived esterases.

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第一作者： Dah Hyun,Jung

第一单位： Department of Microbiology and Immunology, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, South Korea.

作者： Dah Hyun,Jung ^[1] ; Ji Hyun,Yong ^[2] ; Wontae,Hwang ^[1] ; Mi Young,Yoon ^[2] ; Sang Sun,Yoon ^[1]

作者单位： Department of Microbiology and Immunology, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, South Korea. ^[1] Brain Korea 21 PLUS Project for Medical Sciences, Yonsei University College of Medicine, Seoul, Republic of Korea. ^[2] Severance Biomedical Science Institute, Yonsei University College of Medicine, Seoul, Republic of Korea. ^[3] Department of Microbiology and Immunology, Yonsei University College of Medicine, 50-1 Yonsei-ro, Seodaemun-gu, Seoul, 03722, South Korea. sangsun_yoon@yuhs.ac. ^[4] Brain Korea 21 PLUS Project for Medical Sciences, Yonsei University College of Medicine, Seoul, Republic of Korea. sangsun_yoon@yuhs.ac. ^[5] Severance Biomedical Science Institute, Yonsei University College of Medicine, Seoul, Republic of Korea. sangsun_yoon@yuhs.ac. ^[6] Institute for Immunology and Immunological Diseases, Yonsei University College of Medicine, Seoul, Republic of Korea. sangsun_yoon@yuhs.ac. ^[7]

关键词 Bacteroidales Butyrate Clostridiales Colitis Esterase Inflammatory bowel disease (IBD)Metagenomic library Microbiome Prodrug Tributyrin

DOI 10.1186/s13036-021-00259-4

PMID 33676548

发布时间 2021-03-12

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