Microbiome Profile and Molecular Pathways Alterations in Gastrointestinal Tract by Hydrogen Sulfide-Releasing Nonsteroidal Anti-Inflammatory Drug (ATB-352): Insight into Possible Safer Polypharmacy.

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作者： Urszula,Głowacka ^[1] ; Katarzyna,Magierowska ^[1] ; Dagmara,Wójcik ^[1] ; Jerzy,Hankus ^[2] ; Małgorzata,Szetela ^[1] ; Jakub,Cieszkowski ^[1] ; Edyta,Korbut ^[1] ; Aleksandra,Danielak ^[1] ; Marcin,Surmiak ^[1] ; Anna,Chmura ^[3] ; John L,Wallace ^[1] ; Marcin,Magierowski ^[4]

作者单位： Department of Physiology, Jagiellonian University Medical College, Cracow, Poland. ^[1] Department of Pathomorphology, Jagiellonian University Medical College, Cracow, Poland. ^[2] Department of Internal Medicine, Jagiellonian University Medical College, Cracow, Poland. ^[3] Department of Physiology and Pharmacology, University of Calgary, Calgary, Canada. ^[4]

关键词 ATB-352 gastrointestinal toxicity and oxidation hydrogen sulfide intestinal microbiome profile ketoprofen

主题词动物(Animals);消炎药, 非甾类(Anti-Inflammatory Agents, Non-Steroidal);胃肠道(Gastrointestinal Tract);人类(Humans);硫化氢(Hydrogen Sulfide);哺乳动物(Mammals);多种药物疗法(Polypharmacy)

DOI 10.1089/ars.2020.8240

PMID 33678013

发布时间 2022-04-05

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