Global Profiling of Lysine Accessibility to Evaluate Protein Structure Changes in Alzheimer's Disease.-论文-万方医学网

第一作者： Kaiwen,Yu

第一单位： Departments of Structural Biology and Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.

作者： Kaiwen,Yu ^[1] ; Mingming,Niu ^[1] ; Hong,Wang ^[2] ; Yuxin,Li ^[2] ; Zhiping,Wu ^[1] ; Bin,Zhang ^[3] ; Vahram,Haroutunian ^[4] ; Junmin,Peng ^[5]

作者单位： Departments of Structural Biology and Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States. ^[1] Center for Proteomics and Metabolomics, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States. ^[2] Department of Genetics and Genomic Sciences, Icahn Institute of Genomics and Multi-scale Biology, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States. ^[3] Departments of Psychiatry and Neuroscience, The Alzheimer's Disease Research Center, Icahn School of Medicine at Mount Sinai, New York, New York 10029, United States.;Mental Illness Research, Education and Clinical Center (MIRECC), James J. Peters VA Medical Center, Bronx, New York 10468, United States. ^[4] Departments of Structural Biology and Developmental Neurobiology, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States.;Center for Proteomics and Metabolomics, St. Jude Children's Research Hospital, Memphis, Tennessee 38105, United States. ^[5]

医学主题词老年人(Aged);老年人, 80以上(Aged, 80 and over);阿尔茨海默病(Alzheimer Disease);动物(Animals);脑化学(Brain Chemistry);色谱法, 液相(Chromatography, Liquid);人类(Humans);指示剂和试剂(Indicators and Reagents);赖氨酸(Lysine);小鼠(Mice);中年人(Middle Aged);神经组织蛋白质类(Nerve Tissue Proteins);肽类(Peptides);蛋白质结合(Protein Binding);蛋白质构象(Protein Conformation);蛋白质加工, 转译后(Protein Processing, Post-Translational);蛋白质组(Proteome);无特异性病原体有机物(Specific Pathogen-Free Organisms);标本制备(Specimen Handling);构效关系(Structure-Activity Relationship);串联质谱法(Tandem Mass Spectrometry);温度(Temperature);时间因素(Time Factors);tau蛋白质类(tau Proteins)

DOI 10.1021/jasms.0c00450

PMID 33683887

发布时间 2021-11-22

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Global Profiling of Lysine Accessibility to Evaluate Protein Structure Changes in Alzheimer's Disease.

Journal of the American Society for Mass Spectrometry

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Global Profiling of Lysine Accessibility to Evaluate Protein Structure Changes in Alzheimer's Disease.

Journal of the American Society for Mass Spectrometry

相似文献

同项目论文

Journal of the American Society for Mass Spectrometry

相关期刊

检索历史清除