Increased Frequency of Dysfunctional Siglec-7-CD57+PD-1+ Natural Killer Cells in Patients With Non-alcoholic Fatty Liver Disease.

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作者： Yuzuru,Sakamoto ^[1] ; Sachiyo,Yoshio ^[2] ; Hiroyoshi,Doi ^[1] ; Taizo,Mori ^[1] ; Michitaka,Matsuda ^[1] ; Hironari,Kawai ^[1] ; Tomonari,Shimagaki ^[1] ; Shiori,Yoshikawa ^[1] ; Yoshihiko,Aoki ^[1] ; Yosuke,Osawa ^[1] ; Yuji,Yoshida ^[1] ; Taeang,Arai ^[3] ; Norio,Itokawa ^[3] ; Masanori,Atsukawa ^[3] ; Takanori,Ito ^[3] ; Takashi,Honda ^[4] ; Yoshihiro,Mise ^[4] ; Yoshihiro,Ono ^[5] ; Yu,Takahashi ^[5] ; Akio,Saiura ^[5] ; Akinobu,Taketomi ^[5] ; Tatsuya,Kanto ^[2]

作者单位： Department of Liver Diseases, The Research Center for Hepatitis and Immunology, National Center for Global Health and Medicine, Tokyo, Japan. ^[1] Department of Gastoenterological Surgery I, Hokkaido University Graduate School of Medicine, Sapporo, Japan. ^[2] Division of Gastroenterology and Hepatology, Department of Internal Medicine, Nippon Medical School, Tokyo, Japan. ^[3] Division of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Nagoya, Japan. ^[4] Department of Hepato-Pancreatic-Biliary Surgery, Japanese Foundation for Cancer Research, Tokyo, Japan. ^[5]

关键词 CD57 NAFLD NK cell PD-1 Siglec mass cytometry (CyTOF)

主题词成年人(Adult);老年人(Aged);抗原, 分化, 髓单核细胞(Antigens, Differentiation, Myelomonocytic);女(雌)性(Female);流式细胞术(Flow Cytometry);人类(Humans);干扰素γ(Interferon-gamma);杀伤细胞, 天然(Killer Cells, Natural);外源凝集素类(Lectins);溶酶体相关膜蛋白质1(Lysosomal-Associated Membrane Protein 1);男(雄)性(Male);中年人(Middle Aged)

DOI 10.3389/fimmu.2021.603133

PMID 33692781

发布时间 2023-12-13

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Frontiers in immunology

2021年12卷

603133页

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Increased Frequency of Dysfunctional Siglec-7<sup>-</sup>CD57<sup>+</sup>PD-1<sup>+</sup> Natural Killer Cells in Patients With Non-alcoholic Fatty Liver Disease.

Frontiers in immunology

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Frontiers in immunology

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Increased Frequency of Dysfunctional Siglec-7<sup>-</sup>CD57<sup>+</sup>PD-1<sup>+</sup> Natural Killer Cells in Patients With Non-alcoholic Fatty Liver Disease.

Frontiers in immunology

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Frontiers in immunology

相关期刊

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