第一单位：
Cambridge Institute of Therapeutic Immunology & Infectious Disease, Cambridge, UK.;Department of Medicine, University of Cambridge, Cambridge, UK.;Division of Infection and Immunity, University College London, London, UK.
作者：
Dami A,Collier [1]
;
Anna,De Marco [2]
;
Isabella A T M,Ferreira [3]
;
Bo,Meng [3]
;
Rawlings P,Datir [1]
;
Alexandra C,Walls [4]
;
Steven A,Kemp [1]
;
Jessica,Bassi [2]
;
Dora,Pinto [2]
;
Chiara,Silacci-Fregni [2]
;
Siro,Bianchi [2]
;
M Alejandra,Tortorici [4]
;
John,Bowen [4]
;
Katja,Culap [2]
;
Stefano,Jaconi [2]
;
Elisabetta,Cameroni [2]
;
Gyorgy,Snell [5]
;
Matteo S,Pizzuto [2]
;
Alessandra Franzetti,Pellanda [6]
;
Christian,Garzoni [6]
;
Agostino,Riva [7]
;
CITIID-NIHR BioResource COVID-19 Collaboration [8]
;
Anne,Elmer [9]
;
Nathalie,Kingston [9]
;
Barbara,Graves [10]
;
Laura E,McCoy [3]
;
Kenneth G C,Smith [11]
;
John R,Bradley [12]
;
Nigel,Temperton [13]
;
Lourdes,Ceron-Gutierrez [14]
;
Gabriela,Barcenas-Morales [15]
;
COVID-19 Genomics UK (COG-UK) Consortium [5]
;
William,Harvey [2]
;
Herbert W,Virgin [2]
;
Antonio,Lanzavecchia [16]
;
Luca,Piccoli [17]
;
Rainer,Doffinger [4]
;
Mark,Wills [18]
;
David,Veesler [19]
;
Davide,Corti ;
Ravindra K,Gupta
作者单位：
Cambridge Institute of Therapeutic Immunology & Infectious Disease, Cambridge, UK.;Department of Medicine, University of Cambridge, Cambridge, UK.;Division of Infection and Immunity, University College London, London, UK.
[1]
Humabs Biomed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland.
[2]
Cambridge Institute of Therapeutic Immunology & Infectious Disease, Cambridge, UK.;Department of Medicine, University of Cambridge, Cambridge, UK.
[3]
Department of Biochemistry, University of Washington, Seattle, WA, USA.
[4]
Vir Biotechnology, San Francisco, CA, USA.
[5]
Clinic of Internal Medicine and Infectious Diseases, Clinica Luganese Moncucco, Lugano, Switzerland.
[6]
Division of Infectious Diseases, Luigi Sacco Hospital, University of Milan, Milan, Italy.
[7]
NIHR Cambridge Clinical Research Facility, Cambridge, UK.
[8]
NIHR Bioresource, Cambridge, UK.
[9]
Division of Infection and Immunity, University College London, London, UK.
[10]
Department of Medicine, University of Cambridge, Cambridge, UK.;NIHR Bioresource, Cambridge, UK.
[11]
University of Kent, Canturbury, UK.
[12]
Department of Clinical Biochemistry and Immunology, Addenbrooke's Hospital, Cambridge, UK.
[13]
Department of Clinical Biochemistry and Immunology, Addenbrooke's Hospital, Cambridge, UK.;Laboratorio de Inmunologia, UNAM, Cuautitlán, Mexico.
[14]
Institute of Biodiversity, University of Glasgow, Glasgow, UK.
[15]
Department of Clinical Biochemistry and Immunology, Addenbrooke's Hospital, Cambridge, UK.;Department of Haematology, University of Cambridge, Cambridge, UK.
[16]
Department of Medicine, University of Cambridge, Cambridge, UK.
[17]
Humabs Biomed SA, a subsidiary of Vir Biotechnology, Bellinzona, Switzerland. dcorti@vir.bio.
[18]
Cambridge Institute of Therapeutic Immunology & Infectious Disease, Cambridge, UK. rkg20@cam.ac.uk.;Department of Medicine, University of Cambridge, Cambridge, UK. rkg20@cam.ac.uk.;Department of Haematology, University of Cambridge, Cambridge, UK. rkg20@cam.ac.uk.;University of KwaZulu Natal, Durban, South Africa. rkg20@cam.ac.uk.;Africa Health Research Institute, Durban, South Africa. rkg20@cam.ac.uk.;Department of Infectious Diseases, Cambridge University Hospitals NHS Trust, Cambridge, UK. rkg20@cam.ac.uk.
[19]
医学主题词
老年人(Aged);老年人, 80以上(Aged, 80 and over);抗体, 单克隆(Antibodies, Monoclonal);抗体, 中和(Antibodies, Neutralizing);抗体, 病毒(Antibodies, Viral);女(雌)性(Female);HEK293细胞(HEK293 Cells);人类(Humans);免疫逃避(Immune Evasion);免疫法, 被动(Immunization, Passive);男(雄)性(Male);中年人(Middle Aged);模型, 分子(Models, Molecular);突变(Mutation);中和试验(Neutralization Tests);疫苗, 合成(Vaccines, Synthetic)
DOI
10.1038/s41586-021-03412-7
PMID
33706364
发布时间
2025-05-30
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