Low immunogenicity of malaria pre-erythrocytic stages can be overcome by vaccination.

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第一作者： Katja,Müller

第一单位： Parasitology Unit, Max Planck Institute for Infection Biology, Berlin, Germany.

作者： Katja,Müller ^[1] ; Matthew P,Gibbins ^[2] ; Mark,Roberts ^[3] ; Arturo,Reyes-Sandoval ^[3] ; Adrian V S,Hill ^[4] ; Simon J,Draper ^[4] ; Kai,Matuschewski ^[4] ; Olivier,Silvie ^[1] ; Julius Clemence R,Hafalla ^[2]

作者单位： Parasitology Unit, Max Planck Institute for Infection Biology, Berlin, Germany. ^[1] Department of Molecular Parasitology, Institute of Biology, Humboldt University, Berlin, Germany. ^[2] Department of Infection Biology, Faculty of Infectious and Tropical Diseases, London School of Hygiene and Tropical Medicine, London, UK. ^[3] Jenner Institute, University of Oxford, Oxford, UK. ^[4] Sorbonne Université, INSERM, CNRS, Centre d'Immunologie et des Maladies Infectieuses, CIMI-Paris, Paris, France. ^[5]

关键词 Plasmodium immunogenicity malaria pre-erythrocytic protective efficacy

主题词动物(Animals);CD8阳性T淋巴细胞(CD8-Positive T-Lymphocytes);疟疾(Malaria);疟疾疫苗(Malaria Vaccines);孢子体(Sporozoites);接种(Vaccination)

DOI 10.15252/emmm.202013390

PMID 33709544

发布时间 2024-02-16

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