Prognostic value of test(s) for O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation for predicting overall survival in people with glioblastoma treated with temozolomide.

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作者： Alexandra,McAleenan ^[1] ; Claire,Kelly ^[1] ; Francesca,Spiga ^[1] ; Ashleigh,Kernohan ^[2] ; Hung-Yuan,Cheng ^[1] ; Sarah,Dawson ^[1] ; Lena,Schmidt ^[3] ; Tomos,Robinson ^[1] ; Sebastian,Brandner ^[2] ; Claire L,Faulkner ^[4] ; Christopher,Wragg ^[5] ; Sarah,Jefferies ^[6] ; Amy,Howell ^[6] ; Luke,Vale ^[7] ; Julian P T,Higgins ^[1] ; Kathreena M,Kurian ^[2]

作者单位： Population Health Sciences, Bristol Medical School, University of Bristol, Bristol, UK. ^[1] Population Health Sciences Institute, Newcastle University, Newcastle upon Tyne, UK. ^[2] NIHR Applied Research Collaboration West (ARC West) , University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK. ^[3] Department of Neurodegenerative Disease, UCL Queen Square Institute of Neurology, London, UK. ^[4] Division of Neuropathology, The National Hospital for Neurology and Neurosurgery, University College London Hospitals NHS Foundation Trust, London, UK. ^[5] Bristol Genetics Laboratory, Pathology Sciences, Southmead Hospital, Bristol, UK. ^[6] Department of Oncology, Addenbrooke's Hospital, Cambridge, UK. ^[7] NIHR Bristol Biomedical Research Centre, University Hospitals Bristol and Weston NHS Foundation Trust, Bristol, UK. ^[8] Bristol Medical School: Brain Tumour Research Centre, Public Health Sciences, University of Bristol, Bristol, UK. ^[9]

主题词成年人(Adult);抗肿瘤药, 烷基化(Antineoplastic Agents, Alkylating);脑肿瘤(Brain Neoplasms);队列研究(Cohort Studies);CpG岛(CpG Islands);DNA甲基化(DNA Methylation);DNA修饰甲基酶类(DNA Modification Methylases);DNA修复酶类(DNA Repair Enzymes);胶质母细胞瘤(Glioblastoma);高通量核苷酸序列分析(High-Throughput Nucleotide Sequencing);人类(Humans);免疫组织化学(Immunohistochemistry);聚合酶链反应(Polymerase Chain Reaction);试验预期值(Predictive Value of Tests);预后(Prognosis);启动区, 遗传(Promoter Regions, Genetic);肿瘤抑制蛋白质类(Tumor Suppressor Proteins)

DOI 10.1002/14651858.CD013316.pub2

PMID 33710615

发布时间 2024-02-28

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The Cochrane database of systematic reviews

2021年3卷

CD013316页

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Prognostic value of test(s) for O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation for predicting overall survival in people with glioblastoma treated with temozolomide.

The Cochrane database of systematic reviews

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The Cochrane database of systematic reviews

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Prognostic value of test(s) for O6-methylguanine-DNA methyltransferase (MGMT) promoter methylation for predicting overall survival in people with glioblastoma treated with temozolomide.

The Cochrane database of systematic reviews

相似文献

The Cochrane database of systematic reviews

相关期刊

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