首页> Current biology : CB> Loss of Hem1 disrupts macrophage function and impacts migration, phagocytosis, and integrin-mediated adhesion.

Loss of Hem1 disrupts macrophage function and impacts migration, phagocytosis, and integrin-mediated adhesion.

导出 LinkOut

翻译打印收藏纠错

第一作者： Stephanie,Stahnke

第一单位： Department of Cell Biology, Helmholtz Centre for Infection Research (HZI), Braunschweig, Germany.

作者： Stephanie,Stahnke ^[1] ; Hermann,Döring ^[2] ; Charly,Kusch ^[3] ; David J J,de Gorter ^[4] ; Sebastian,Dütting ^[3] ; Aleks,Guledani ^[4] ; Irina,Pleines ^[3] ; Michael,Schnoor ^[5] ; Michael,Sixt ^[6] ; Robert,Geffers ^[7] ; Manfred,Rohde ^[8] ; Mathias,Müsken ^[8] ; Frieda,Kage ^[2] ; Anika,Steffen ^[1] ; Jan,Faix ^[9] ; Bernhard,Nieswandt ^[3] ; Klemens,Rottner ^[10] ; Theresia E B,Stradal ^[11]

作者单位： Department of Cell Biology, Helmholtz Centre for Infection Research (HZI), Braunschweig, Germany. ^[1] Zoological Institute, Technische Universität Braunschweig, Braunschweig, Germany. ^[2] Institute of Experimental Biomedicine, University Hospital and Rudolf Virchow Center, University of Würzburg, Würzburg, Germany. ^[3] Institute of Molecular Cell Biology, Westphalian Wilhelms University Münster WWU, Münster, Germany. ^[4] Department for Molecular Biomedicine, Centre for Investigation and Advanced Studies of the National Polytechnic Institute (Cinvestav-IPN), 07360 Mexico City, Mexico. ^[5] Institute of Science and Technology IST Austria, Klosterneuburg, Austria. ^[6] Genome Analytics Group, Helmholtz Center for Infection Research HZI, Braunschweig, Germany. ^[7] Central Facility for Microscopy, Helmholtz Center for Infection Research HZI, Braunschweig, Germany. ^[8] Institute for Biophysical Chemistry, Hannover Medical School MHH, 30625 Hannover, Germany. ^[9] Department of Cell Biology, Helmholtz Centre for Infection Research (HZI), Braunschweig, Germany; Zoological Institute, Technische Universität Braunschweig, Braunschweig, Germany. ^[10] Department of Cell Biology, Helmholtz Centre for Infection Research (HZI), Braunschweig, Germany. Electronic address: theresia.stradal@helmholtz-hzi.de. ^[11]

关键词 Hem1 WAVE regulatory complex WRC adhesion integrin knockout macrophage phagocytosis protrusion rescue