Presynaptic store-operated Ca<sup>2+</sup> entry drives excitatory spontaneous neurotransmission and augments endoplasmic reticulum stress.

导出 OA

翻译打印收藏纠错

作者： Natali L,Chanaday ^[1] ; Elena,Nosyreva ^[2] ; Ok-Ho,Shin ^[1] ; Hua,Zhang ^[3] ; Iltan,Aklan ^[4] ; Deniz,Atasoy ^[5] ; Ilya,Bezprozvanny ^[6] ; Ege T,Kavalali ^[7]

作者单位： Department of Pharmacology, School of Medicine, Vanderbilt University, Nashville, TN 37240-7933, USA. ^[1] Department of Neuroscience, The University of Texas Southwestern Medical Center, Dallas, TX 75390-9111, USA. ^[2] Department of Physiology, The University of Texas Southwestern Medical Center, Dallas, TX 75390-9040, USA. ^[3] Department of Neuroscience and Pharmacology, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA. ^[4] Department of Neuroscience and Pharmacology, Carver College of Medicine, University of Iowa, Iowa City, IA 52242, USA; Iowa Neuroscience Institute, University of Iowa, Iowa City, IA 52242, USA; FOE Diabetes Research Center, University of Iowa, Iowa City, IA 52242, USA. ^[5] Department of Physiology, The University of Texas Southwestern Medical Center, Dallas, TX 75390-9040, USA; Laboratory of Molecular Neurodegeneration, Peter the Great St Petersburg State Polytechnic University, St. Petersburg, Russia. ^[6] Department of Pharmacology, School of Medicine, Vanderbilt University, Nashville, TN 37240-7933, USA; Vanderbilt Brain Institute, Vanderbilt University, Nashville, TN 37240-7933, USA. Electronic address: ege.kavalali@vanderbilt.edu. ^[7]

关键词 Orai STIM2 calcium endoplasmic reticulum stress spontaneous neurotrasnmission store operated calcium entry synaptic vesicle synaptotagmin-7