A landmark-free morphometrics pipeline for high-resolution phenotyping: application to a mouse model of Down syndrome.

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第一作者： Nicolas,Toussaint

第一单位： School of Biomedical Engineering and Imaging Sciences, King's College London, UK.

作者： Nicolas,Toussaint ^[1] ; Yushi,Redhead ^[2] ; Marta,Vidal-García ^[3] ; Lucas,Lo Vercio ^[3] ; Wei,Liu ^[3] ; Elizabeth M C,Fisher ^[4] ; Benedikt,Hallgrímsson ^[5] ; Victor L J,Tybulewicz ^[6] ; Julia A,Schnabel ^[1] ; Jeremy B A,Green ^[7]

作者单位： School of Biomedical Engineering and Imaging Sciences, King's College London, UK. ^[1] Centre for Craniofacial Biology & Regeneration, King's College London, UK.;The Francis Crick Institute, London NW1 1AT, UK. ^[2] Department of Cell Biology & Anatomy, University of Calgary, Calgary AB T2N 4N1, Canada. ^[3] Department of Neurodegenerative Disease, Institute of Neurology, University College London, London WC1N 3BG, UK. ^[4] Department of Cell Biology & Anatomy, University of Calgary, Calgary AB T2N 4N1, Canada bhallgri@ucalgary.ca victor.t@crick.ac.uk jeremy.green@kcl.ac.uk. ^[5] The Francis Crick Institute, London NW1 1AT, UK bhallgri@ucalgary.ca victor.t@crick.ac.uk jeremy.green@kcl.ac.uk.;Department of Immunology & Inflammation, Imperial College London, London W12 0NN, UK. ^[6] Centre for Craniofacial Biology & Regeneration, King's College London, UK bhallgri@ucalgary.ca victor.t@crick.ac.uk jeremy.green@kcl.ac.uk. ^[7]

关键词 Craniofacial Cranium Down syndrome Morphometrics Mouse model Phenotyping