Integrated cross-study datasets of genetic dependencies in cancer.

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作者： Clare,Pacini ^[1] ; Joshua M,Dempster ^[2] ; Isabella,Boyle ^[3] ; Emanuel,Gonçalves ^[3] ; Hanna,Najgebauer ^[1] ; Emre,Karakoc ^[1] ; Dieudonne,van der Meer ^[2] ; Andrew,Barthorpe ^[4] ; Howard,Lightfoot ^[1] ; Patricia,Jaaks ^[2] ; James M,McFarland ^[1] ; Mathew J,Garnett ^[1] ; Aviad,Tsherniak ^[1] ; Francesco,Iorio ^[1]

作者单位： Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK. ^[1] Open Targets, Wellcome Genome Campus, Hinxton, Cambridge, UK. ^[2] Broad Institute of MIT and Harvard, Cambridge, MA, USA. ^[3] European Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Cambridge, UK. ^[4] Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridge, UK. francesco.iorio@fht.org. ^[5] Open Targets, Wellcome Genome Campus, Hinxton, Cambridge, UK. francesco.iorio@fht.org. ^[6] Human Technopole, Milano, Italy. francesco.iorio@fht.org. ^[7]

主题词细胞系, 肿瘤(Cell Line, Tumor);DNA拷贝数变异(DNA Copy Number Variations);基因, 必要(Genes, Essential);基因组学(Genomics);人类(Humans);肿瘤(Neoplasms)

DOI 10.1038/s41467-021-21898-7

PMID 33712601

发布时间 2024-01-04

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