首页> Frontiers in immunology> PLGA Nanoparticles Co-encapsulating NY-ESO-1 Peptides and IMM60 Induce Robust CD8 and CD4 T Cell and B Cell Responses.

PLGA Nanoparticles Co-encapsulating NY-ESO-1 Peptides and IMM60 Induce Robust CD8 and CD4 T Cell and B Cell Responses.

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第一作者： Yusuf,Dölen

第一单位： Department of Tumor Immunology, Radboud University Medical Center, Radboud Institute for Molecular Life Sciences, Nijmegen, Netherlands.;Oncode Institute, Nijmegen, Netherlands.

作者： Yusuf,Dölen ^[1] ; Uzi,Gileadi ^[2] ; Ji-Li,Chen ^[2] ; Michael,Valente ^[3] ; Jeroen H A,Creemers ^[1] ; Eric A W,Van Dinther ^[1] ; N Koen,van Riessen ^[4] ; Eliezer,Jäger ^[5] ; Martin,Hruby ^[5] ; Vincenzo,Cerundolo ^[2] ; Mustafa,Diken ^[6] ; Carl G,Figdor ^[1] ; I Jolanda M,de Vries ^[4]

作者单位： Department of Tumor Immunology, Radboud University Medical Center, Radboud Institute for Molecular Life Sciences, Nijmegen, Netherlands.;Oncode Institute, Nijmegen, Netherlands. ^[1] Medical Research Council Human Immunology Unit, Radcliffe Department of Medicine, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, United Kingdom. ^[2] Department of Tumor Immunology, Radboud University Medical Center, Radboud Institute for Molecular Life Sciences, Nijmegen, Netherlands.;Aix Marseille Univ, CNRS, INSERM, CIML, Centre d'Immunologie de Marseille-Luminy, Marseille, France. ^[3] Department of Tumor Immunology, Radboud University Medical Center, Radboud Institute for Molecular Life Sciences, Nijmegen, Netherlands. ^[4] Institute of Macromolecular Chemistry v. v. i., Academy of Sciences of the Czech Republic, Prague, Czechia. ^[5] TRON - Translational Oncology at the University Medical Center of the Johannes Gutenberg University Mainz gGmbH, Mainz, Germany. ^[6]

关键词 B cell epitope CD4 T cell CD8 T cell IMM60 NY-ESO-1 PLGA nanoparticle iNKT cell peptide vaccine