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Characterization of a novel OX40 ligand and CD40 ligand-expressing oncolytic adenovirus used in the PeptiCRAd cancer vaccine platform.

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第一作者： Erkko,Ylösmäki

第一单位： Laboratory of Immunovirotherapy, Drug Research Program, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland.;TRIMM, Translational Immunology Research Program, University of Helsinki, Finland.

作者： Erkko,Ylösmäki ^[1] ; Leena,Ylösmäki ^[2] ; Manlio,Fusciello ^[1] ; Beatriz,Martins ^[1] ; Petra,Ahokas ^[2] ; Hanne,Cojoc ^[2] ; Arttu,Uoti ^[1] ; Sara,Feola ^[1] ; Anna,Kreutzman ^[1] ; Tuuli,Ranki ^[2] ; Julia,Karbach ^[3] ; Tapani,Viitala ^[4] ; Petri,Priha ^[2] ; Elke,Jäger ^[3] ; Sari,Pesonen ^[2] ; Vincenzo,Cerullo ^[5]

作者单位： Laboratory of Immunovirotherapy, Drug Research Program, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland.;TRIMM, Translational Immunology Research Program, University of Helsinki, Finland. ^[1] Valo Therapeutics Oy, Helsinki, Finland. ^[2] Department of Oncology and Hematology, Krankenhaus Nordwest, Frankfurt am Main, Germany. ^[3] Pharmaceutical Biophysics Research Group, Drug Research Program, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland. ^[4] Laboratory of Immunovirotherapy, Drug Research Program, Faculty of Pharmacy, University of Helsinki, Helsinki, Finland.;TRIMM, Translational Immunology Research Program, University of Helsinki, Finland.;iCAN Digital Precision Cancer Medicine Flagship, University of Helsinki, Helsinki, Finland.;Department of Molecular Medicine and Medical Biotechnology and CEINGE, Naples University, 24 Federico II, 80131 Naples, Italy. ^[5]

关键词 CD40L OX40L PeptiCRAd T cell activation oncolytic vaccine

DOI 10.1016/j.omto.2021.02.006

PMID 33718594

发布时间 2021-03-16

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Molecular therapy oncolytics

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Molecular therapy oncolytics

2021年20卷

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Characterization of a novel OX40 ligand and CD40 ligand-expressing oncolytic adenovirus used in the PeptiCRAd cancer vaccine platform.

Molecular therapy oncolytics

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Characterization of a novel OX40 ligand and CD40 ligand-expressing oncolytic adenovirus used in the PeptiCRAd cancer vaccine platform.

Molecular therapy oncolytics

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Molecular therapy oncolytics

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