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首页> Ecotoxicology and environmental safety> Short-term perfluorooctane sulfonate exposure impairs Leydig cell regeneration in the adult rat testis via targeting hedgehog signaling.

Short-term perfluorooctane sulfonate exposure impairs Leydig cell regeneration in the adult rat testis via targeting hedgehog signaling.

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作者： Baiping,Mao ^[1] ; Chao,Li ^[2] ; Zina,Wen ^[3] ; Huitao,Li ^[1] ; Yiyan,Wang ^[1] ; Lanlan,Chen ^[1] ; Qingquan,Lian ^[4] ; Ren-Shan,Ge ^[5]

作者单位： Department of Anesthesiology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, 109 Xueyuan West Road, Wenzhou, Zhejiang 325027, China. ^[1] Center of Scientific Research, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, 109 Xueyuan West Road, Wenzhou, Zhejiang 325027, China. ^[2] Xi'nan Gynecological Hospital, Chengdu, Sichuan, China. ^[3] Department of Anesthesiology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, 109 Xueyuan West Road, Wenzhou, Zhejiang 325027, China. Electronic address: wzmzlqq@163.com. ^[4] Department of Anesthesiology, The Second Affiliated Hospital and Yuying Children's Hospital of Wenzhou Medical University, 109 Xueyuan West Road, Wenzhou, Zhejiang 325027, China. Electronic address: r_ge@yahoo.com. ^[5]

关键词 Hedgehog signaling Leydig cell regeneration Leydig cells Perfluorooctane sulfonate Stem cells Steroidogenesis

主题词链烷磺酸类(Alkanesulfonic Acids);动物(Animals);细胞分化(Cell Differentiation);细胞增殖(Cell Proliferation);氟碳化合物(Fluorocarbons);猬蛋白质类(Hedgehog Proteins);男(雄)性(Male);甲磺酸盐类(Mesylates);大鼠, Sprague-Dawley(Rats, Sprague-Dawley);再生(Regeneration);信号传导(Signal Transduction);睾丸(Testis);睾酮(Testosterone);大鼠(Rats)

DOI 10.1016/j.ecoenv.2021.112121

PMID 33721578

发布时间 2024-02-26

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Ecotoxicology and environmental safety

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