Thin-Layer-Agar-Based Direct Phenotypic Drug Susceptibility Testing on Sputum in Eswatini Rapidly Detects Mycobacterium tuberculosis Growth and Rifampicin Resistance Otherwise Missed by WHO-Endorsed Diagnostic Tests.

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作者： E,Ardizzoni ^[1] ; E,Ariza ^[2] ; D,Mulengwa ^[3] ; Q,Mpala ^[3] ; R,de La Tour ^[4] ; G,Maphalala ^[5] ; F,Varaine ^[6] ; B,Kerschberger ^[4] ; P,Graulus ^[7] ; A L,Page ^[8] ; S,Niemann ^[9] ; V,Dreyer ^[10] ; A,Van Deun ^[9] ; T,Decroo ^[10] ; L,Rigouts ^[7] ; B C,de Jong ^[7]

作者单位： Institute of Tropical Medicine, Antwerp, Belgium eardizzoni@itg.be. ^[1] Infectious Diseases Service, Hospital Clinic-IDIBAPS, Barcelona, Spain. ^[2] Médecins Sans Frontières, Mbabane, Eswatini. ^[3] Médecins Sans Frontières, Geneva, Switzerland. ^[4] Ministry of Health (NRL), Mbabane, Eswatini. ^[5] Médecins Sans Frontières, Paris, France. ^[6] Institute of Tropical Medicine, Antwerp, Belgium. ^[7] Epicentre, Paris, France. ^[8] Molecular and Experimental Mycobacteriology, Research Center Borstel, Borstel, Germany. ^[9] German Center for Infection Research (DZIF), Borstel, Germany. ^[10] Research Foundation Flanders, Brussels, Belgium. ^[11] University of Antwerp, Antwerp, Belgium. ^[12]

关键词 MDR TLA XDR Xpert MTB/RIF resistance detection rpoB I491F mutant tuberculosis