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Effect of Intermediate-Dose vs Standard-Dose Prophylactic Anticoagulation on Thrombotic Events, Extracorporeal Membrane Oxygenation Treatment, or Mortality Among Patients With COVID-19 Admitted to the Intensive Care Unit: The INSPIRATION Randomized Clinical Trial.

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作者单位: Cardiovascular Intervention Research Center, Rajaie Cardiovascular, Medical, and Research Center, Iran University of Medical Sciences, Tehran, Iran. [1] Clinical Trial Center, Rajaie Cardiovascular, Medical, and Research Center, Iran University of Medical Sciences, Tehran, Iran. [2] Tehran Heart Center, Tehran University of Medical Sciences, Tehran, Iran. [3] Tuberculosis and Lung Diseases Research Center, Tabriz University of Medical Sciences, Tabriz, Iran. [4] Tobacoo Prevention and control Research center, National Research institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran. [5] Lung Transplantation Research Center, Department of Cardiology, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran. [6] Anesthesiology and Intensive Care, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran. [7] Firouzgar hospital, Department of internal medicine, Iran University of Medical Sciences, Tehran, Iran. [8] Research Center for Prevention of Cardiovascular Disease, Institute of Endocrinology & Metabolism, Iran University of Medical Sciences, Tehran, Iran. [9] Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran. [10] Department of Anesthesiology, School of Medicine Anesthesiology Research Center Shahid Modarres Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran. [11] School of Medicine, Department of Internal Medicine, Shariati Hospital, Tehran, Iran. [12] Student Research Committee, Iran University of Medical Sciences, Tehran, Iran. [13] Department of Pharmacotherapy, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran. [14] Rasoul-e-Akram Hospital, Iran University of Medical Sciences, Tehran, Iran. [15] Chronic Respiratory Disease Research Center, Masih Daneshvari Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran. [16] Department of Pharmacotherapy, Faculty of Pharmacy, Kermanshah University of Medical Sciences, Kermanshah, Iran. [17] School of Pharmacy, Tehran University of Medical Sciences, Tehran, Iran. [18] Rajaie Cardiovascular Medical and Research Center, Iran university of Medical sciences, Tehran, Iran. [19] School of Medicine, Department of Pulmonary and Critical Care, Shariati Hospital, Tehran, Iran. [20] Advanced Thoracic Research Center, Tehran University of Medical Sciences, Tehran, Iran. [21] Cardiovascular Research Center, Shahid Beheshti University of Medical Sciences, Tehran, Iran. [22] Shahid Dr Labbafinejad Hospital, Shahid Beheshti University of Medical Sciences, Tehran, Iran. [23] Respiratory Department, Hospital Ramón y Cajal (IRYCIS), Madrid, Spain. [24] Medicine Department, Universidad de Alcalá (IRYCIS), Madrid, Spain. [25] CIBER Enfermedades Respiratorias (CIBERES), Madrid, Spain. [26] Cardiovascular Research Foundation (CRF), New York, New York. [27] Division of Cardiology, Columbia University Irving Medical Center/NewYork-Presbyterian Hospital, New York, New York. [28] Yale/YNHH Center for Outcomes Research & Evaluation, New Haven, Connecticut. [29] Department of Internal Medicine, Hospital Germans Trias i Pujol, Badalona, Barcelona, Universidad Católica de Murcia, Murcia, Spain. [30] Cardiovascular Medicine Division, Brigham and Women's Hospital, Harvard Medical School, Boston, Massachusetts. [31] School of Pharmacy, Department of Pharmacotherapy and Outcome Science, Virginia Commonwealth University, Richmond, Virginia. [32] School of Pharmacy, Pauley Heart Center, Division of Cardiology, Department of Internal Medicine, Virginia Commonwealth University, Richmond, Virginia. [33] College of Pharmacy, University of Nebraska Medical Center, Omaha. [34] The Zena and Michael A. Wiener Cardiovascular Institute, Icahn School of Medicine at Mount Sinai, New York, New York. [35] Liverpool Centre for Cardiovascular Science, University of Liverpool and Liverpool Heart & Chest Hospital, Liverpool, United Kingdom. [36] Aalborg University, Aalborg, Denmark. [37] Section of Cardiovascular Medicine, Department of Internal Medicine, Yale School of Medicine, New Haven, Connecticut. [38] Department of Health Policy and Administration, Yale School of Public Health, New Haven, Connecticut. [39]
DOI 10.1001/jama.2021.4152
PMID 33734299
发布时间 2021-09-20
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2021年325卷16期

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