Gas chromatography-mass spectrometry based <sup>18</sup>O stable isotope labeling of Krebs cycle intermediates.

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作者： Cemil Can,Eylem ^[1] ; İpek,Baysal ^[2] ; Acelya,Erikci ^[3] ; Samiye,Yabanoglu-Ciftci ^[4] ; Song,Zhang ^[5] ; Sedef,Kır ^[6] ; Andre,Terzic ^[7] ; Petras,Dzeja ^[8] ; Emirhan,Nemutlu ^[9]

作者单位： Hacettepe University, Faculty of Pharmacy, Department of Analytical Chemistry, Ankara, Turkey. Electronic address: cemilcaneylem@gmail.com. ^[1] Hacettepe University, Hacettepe University, Vocational School of Health Services, Ankara, Turkey. Electronic address: ipekbysl@gmail.com. ^[2] Lokman Hekim University, Faculty of Pharmacy, Department of Biochemistry, Ankara, Turkey. Electronic address: acelya.erikci@lokmanhekim.edu.tr. ^[3] Hacettepe University, Faculty of Pharmacy, Department of Biochemistry, Ankara, Turkey. Electronic address: samiye@hacettepe.edu.tr. ^[4] Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA. Electronic address: zhang.song@mayo.edu. ^[5] Hacettepe University, Faculty of Pharmacy, Department of Analytical Chemistry, Ankara, Turkey. Electronic address: sekir@hacettepe.edu.tr. ^[6] Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA. Electronic address: terzic.andre@mayo.edu. ^[7] Department of Cardiovascular Medicine, Mayo Clinic, Rochester, MN, USA. Electronic address: dzeja.petras@mayo.edu. ^[8] Hacettepe University, Faculty of Pharmacy, Department of Analytical Chemistry, Ankara, Turkey. Electronic address: enemutlu@hacettepe.edu.tr. ^[9]

关键词 (18)O stable isotope labeling Citric acid cycle Colon adenocarcinoma Gas chromatography-mass spectrometry Krebs cycle Warburg effect

主题词 Caco-2细胞(Caco-2 Cells);柠檬酸循环(Citric Acid Cycle);气相色谱-质谱法(Gas Chromatography-Mass Spectrometry);人类(Humans);同位素标记(Isotope Labeling);代谢组学(Metabolomics)

DOI 10.1016/j.aca.2021.338325

PMID 33736808

发布时间 2021-05-14

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