Repurposing of the Antiepileptic Drug Levetiracetam to Restrain Neuroendocrine Prostate Cancer and Inhibit Mast Cell Support to Adenocarcinoma.
第一作者:
Roberta,Sulsenti
第一单位:
Molecular Immunology Unit, Department of Research, Fondazione Istituto di Ricerca e Cura a Carattere Scientifico (IRCCS) Istituto Nazionale dei Tumori, Milan, Italy.
作者:
医学主题词
动物(Animals);抗惊厥药(Anticonvulsants);抗肿瘤药(Antineoplastic Agents);癌, 神经内分泌(Carcinoma, Neuroendocrine);细胞脱颗粒(Cell Degranulation);细胞分化(Cell Differentiation);细胞增殖(Cell Proliferation);药物重新定位(Drug Repositioning);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);人类(Humans);男(雄)性(Male);肥大细胞(Mast Cells);基质金属蛋白酶9(Matrix Metalloproteinase 9);膜糖蛋白类(Membrane Glycoproteins);小鼠, 近交C57BL(Mice, Inbred C57BL);小鼠, 转基因(Mice, Transgenic);肿瘤, 实验性(Neoplasms, Experimental);神经组织蛋白质类(Nerve Tissue Proteins);前列腺肿瘤(Prostatic Neoplasms);肿瘤细胞, 培养的(Tumor Cells, Cultured);小鼠(Mice)
DOI
10.3389/fimmu.2021.622001
PMID
33737929
发布时间
2024-02-26
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Frontiers in immunology
622001页
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