Using Individualized Patient Data for Prediction of Population Dosing Recommendations Versus Predictions of Individualized Patient Dosing.

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第一作者： Leslie Z,Benet

第一单位： Department of Bioengineering and Therapeutic Sciences, Schools of Pharmacy and Medicine, University of California San Francisco, San Francisco, California, USA.

作者： Leslie Z,Benet ^[1]

作者单位： Department of Bioengineering and Therapeutic Sciences, Schools of Pharmacy and Medicine, University of California San Francisco, San Francisco, California, USA. ^[1]

关键词 CYP3A4 PBPK drug metabolism modeling and simulation pharmacokinetics and drug metabolism population pharmacokinetics

主题词计算机模拟(Computer Simulation);剂量效应关系, 药物(Dose-Response Relationship, Drug);人类(Humans);模型, 生物学(Models, Biological);肾透析(Renal Dialysis);肾功能不全(Renal Insufficiency)

DOI 10.1002/jcph.1859

PMID 33742720

发布时间 2021-12-20

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