Histology-based molecular profiling improves mutation detection for advanced thyroid cancer.

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作者： Markus,Eszlinger ^[1] ; Moosa,Khalil ^[2] ; Aaron Hill,Gillmor ^[3] ; Helen,Huang ^[4] ; Paul,Stewardson ^[5] ; John B,McIntyre ^[6] ; Sorana,Morrissy ^[7] ; Ralf,Paschke ^[8]

作者单位： Departments of Oncology, Pathology and Laboratory Medicine, Biochemistry and Molecular Biology, and Arnie Charbonneau Cancer Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada. ^[1] Institute of Pathology, University Hospital Halle, Halle, Germany. ^[2] Department of Pathology and Laboratory Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada. ^[3] Department of Graduate Sciences and Arnie Charbonneau Cancer Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada. ^[4] Department of Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada. ^[5] Department of Medical Science and Arnie Charbonneau Cancer Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada. ^[6] Precision Oncology Hub Laboratory, Alberta Health Services, Tom Baker Cancer Centre, Calgary, Alberta, Canada. ^[7] Department of Biochemistry and Molecular Biology, and Arnie Charbonneau Cancer Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada. ^[8] Departments of Medicine, Oncology, Pathology and Laboratory Medicine, Biochemistry and Molecular Biology, and Arnie Charbonneau Cancer Institute, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada. ^[9]

关键词 cancer molecular profile radioiodine resistance thyroid whole exome sequencing