Simvastatin inhibits oral squamous cell carcinoma by targeting TMEM16A Ca<sup>2+</sup>-activated chloride channel.
第一作者:
Hechen,Wang
第一单位:
Liaoning Provincial Key Laboratory of Oral Diseases, Department of Oromaxillofacial-Head and Neck Surgery, School and Hospital of Stomatology, China Medical University, 117 Nanjing Bei Jie, Heping District, Shenyang,, 110002, Liaoning, China.;Department of Ion Channel Pharmacology, School of Pharmacy, China Medical University, No.77 Puhe Road, Shenyang North New Area, Shenyang, 110122, Liaoning Province, China.
作者:
主题词
癌, 鳞状细胞(Carcinoma, Squamous Cell);细胞增殖(Cell Proliferation);细胞, 培养的(Cells, Cultured);减量调节(Down-Regulation);基因表达调控, 肿瘤(Gene Expression Regulation, Neoplastic);人类(Humans);离子通道闸门(Ion Channel Gating);口腔肿瘤(Mouth Neoplasms);肿瘤蛋白质类(Neoplasm Proteins);肿瘤分期(Neoplasm Staging);斯伐他汀(Simvastatin)
DOI
10.1007/s00432-021-03575-w
PMID
33755783
发布时间
2021-05-25
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