Chemical inhibitors of the conserved bacterial transcriptional regulator DksA1 suppressed quorum sensing-mediated virulence of Pseudomonas aeruginosa.

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作者： Kyung Bae,Min ^[1] ; Wontae,Hwang ^[1] ; Kang-Mu,Lee ^[2] ; June Beom,Kim ^[1] ; Sang Sun,Yoon ^[3]

作者单位： Department of Microbiology and Immunology, Yonsei University College of Medicine, Seoul, Korea; Brain Korea 21 PLUS Project for Medical Sciences, Yonsei University College of Medicine, Seoul, Korea. ^[1] Department of Microbiology and Immunology, Yonsei University College of Medicine, Seoul, Korea. ^[2] Department of Microbiology and Immunology, Yonsei University College of Medicine, Seoul, Korea; Brain Korea 21 PLUS Project for Medical Sciences, Yonsei University College of Medicine, Seoul, Korea; Institute for Immunology and Immunological Diseases, Yonsei University College of Medicine, Seoul, Korea; Severance Biomedical Science Institute, Yonsei University College of Medicine, Seoul, Korea. Electronic address: sangsun_yoon@yuhs.ac. ^[3]

关键词 DksA1 Pseudomonas aeruginosa quorums sensing stringent response transcriptional factor virulence factor

主题词动物(Animals);抗菌药(Anti-Bacterial Agents);细菌蛋白质类(Bacterial Proteins);细胞系(Cell Line);保守序列(Conserved Sequence);小鼠(Mice);突变(Mutation);铜绿假单胞菌(Pseudomonas aeruginosa);群体感应(Quorum Sensing);毒力(Virulence)

DOI 10.1016/j.jbc.2021.100576

PMID 33757766

发布时间 2021-08-18

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The Journal of biological chemistry

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Chemical inhibitors of the conserved bacterial transcriptional regulator DksA1 suppressed quorum sensing-mediated virulence of Pseudomonas aeruginosa.

The Journal of biological chemistry

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The Journal of biological chemistry

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Chemical inhibitors of the conserved bacterial transcriptional regulator DksA1 suppressed quorum sensing-mediated virulence of Pseudomonas aeruginosa.

The Journal of biological chemistry

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The Journal of biological chemistry

相关期刊

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