换一批
换一批An injectable micelle-hydrogel hybrid for localized and prolonged drug delivery in the management of renal fibrosis.
作者：
关键词
Anti-TGFβ antibodyBSA, bovine serum albuminCLT, celastrolCelastrolControlled releaseCy5.5-NHS, cyanine 5.5-N-hydroxysuccinimideDAPI, 4′,6-diamidino-2-phenylindoleDEX, dexamethasoneDiD, 1,1′-dioctadecyl-3,3,3′,3′-tetramethylindodicarbocyanineperchlorateECM, extracellular matrixEDCI, carbodiimide hydrochlorideESR, equilibrium swelling ratioFITC, fluorescein isothiocyanateG", the loss modulusG', storage modulusHA, hyaluronic acidHASH, thiolated hyaluronic acidHydrogelIL-1β, interleukin 1βIL-6, interleukin 6InflammationLocalized therapyMOD, mean optical densityNHS, N-hydroxysuccinimidePDI, polydispersity indexRIF, renal interstitial fibrosisRSR, real-time swelling ratioRenal fibrosisSD, standard deviationSEM, scanning electron microscopyTEM, transmission electron microscopyTGF-β1, transforming growth factor β1TNF-α, tumor necrosis factor αTUNEL, terminal deoxynucleotidyl transferase dUTP nick end labellingUUO, unilateral ureteral obstructionbis-F127-MA, bis-F127-methacrylateiNOS, nitric oxide synthaseα-SMA, α-smooth muscle actin“Plum?pudding” structure
DOI
10.1016/j.apsb.2020.10.016
PMID
33777685
发布时间
2021-03-30
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Acta pharmaceutica Sinica. B
2021年11卷3期
835-847页
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