首页> Toxicology reports> Polychlorinated biphenyls altered gut microbiome in CAR and PXR knockout mice exhibiting toxicant-associated steatohepatitis.

Polychlorinated biphenyls altered gut microbiome in CAR and PXR knockout mice exhibiting toxicant-associated steatohepatitis.

导出 LinkOut

翻译打印收藏纠错

第一作者： Banrida,Wahlang

第一单位： UofL Superfund Research Center, University of Louisville, Louisville, KY, USA.;Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, School of Medicine, University of Louisville, Louisville, KY, USA.;Department of Pharmacology & Toxicology, School of Medicine, University of Louisville, Louisville, KY, USA.

作者： Banrida,Wahlang ^[1] ; Nicholas C,Alexander ^[2] ; Xiaohong,Li ^[3] ; Eric C,Rouchka ^[4] ; Irina A,Kirpich ^[5] ; Matthew C,Cave ^[6]

作者单位： UofL Superfund Research Center, University of Louisville, Louisville, KY, USA.;Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, School of Medicine, University of Louisville, Louisville, KY, USA.;Department of Pharmacology & Toxicology, School of Medicine, University of Louisville, Louisville, KY, USA. ^[1] School of Medicine, University of Louisville, Louisville, KY, USA. ^[2] Department of Anatomical Sciences and Neurobiology, School of Medicine, University of Louisville, Louisville, KY, USA.;KBRIN Bioinformatics Core, University of Louisville, Louisville, KY, USA. ^[3] KBRIN Bioinformatics Core, University of Louisville, Louisville, KY, USA.;Department of Computer Science and Engineering, J.B. Speed School of Engineering, University of Louisville, Louisville, KY, USA. ^[4] Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, School of Medicine, University of Louisville, Louisville, KY, USA.;Department of Pharmacology & Toxicology, School of Medicine, University of Louisville, Louisville, KY, USA. ^[5] UofL Superfund Research Center, University of Louisville, Louisville, KY, USA.;Division of Gastroenterology, Hepatology, and Nutrition, Department of Medicine, School of Medicine, University of Louisville, Louisville, KY, USA.;Department of Pharmacology & Toxicology, School of Medicine, University of Louisville, Louisville, KY, USA.;Department of Biochemistry & Molecular Genetics, School of Medicine, University of Louisville, Louisville, KY, USA.;Robley Rex Veterans Affairs Medical Center, Louisville, KY, USA. ^[6]

关键词 ACHS, anniston community healthy survey AhR, arylhydrocarbon receptor Aroclor1260 CAR, constitutive androstane receptor Camp, cathelicidin anti-microbial peptide Cdh5, adhesion molecule VE-cadherin Cldn, claudin Fasn, fatty acid synthase Fgf15, fibroblast growth factor 15 Gut-liver HFD, high fat diet HOMA, homeostasis model assessment IBD, inflammatory bowel diseases LDA, linear discriminant analysis LEfSe, linear discriminant analysis effect size Microbiome Muc, mucin NAFLD NAFLD, nonalcoholic fatty liver disease NASH, nonalcoholic steatohepatitis OTU, operational taxonomic unit Ocln, occludin PCBs PCBs, polychlorinated biphenyls PXR, pregnane-xenobiotic receptor Pck1, phosphoenolpyruvate carboxykinase 1 Ppara, peroxisome-proliferator activated receptor alpha RER, respiratory exchange rate Reg3g, regenerating islet-derived protein 3-gamma TASH TASH, toxicant-associated steatohepatitis Tff3, trefoil factor 3 Tjp1, tight junction protein 1 Tnfa, tumor necrosis factor WT, wildtype

DOI 10.1016/j.toxrep.2021.03.010

PMID 33777700

发布时间 2026-05-12

基金项目

P30 ES030283/ES/NIEHS NIH HHS/United States R01 AA024102/AA/NIAAA NIH HHS/United States

翻译满意度评价：

准确一般字义偏差语意偏离译文作用小提交

浏览0

Toxicology reports

2021年8卷

536-547页

相似文献

中文期刊
外文期刊
学位论文
会议论文

浏览0

点击下载本期目录封面

Toxicology reports

2021年8卷

536-547页

检索历史清除

Polychlorinated biphenyls altered gut microbiome in CAR and PXR knockout mice exhibiting toxicant-associated steatohepatitis.

Toxicology reports

相似文献

同项目论文

Toxicology reports

相关期刊

参考文献：
指定格式：	NoteExpress EndNote RefWorks NoteFirst

检索历史 清除

Polychlorinated biphenyls altered gut microbiome in CAR and PXR knockout mice exhibiting toxicant-associated steatohepatitis.

Toxicology reports

相似文献

同项目论文

Toxicology reports

相关期刊

检索历史清除