Systematic identification of plausible pathways to potential harm via problem formulation for investigational releases of a population suppression gene drive to control the human malaria vector Anopheles gambiae in West Africa.

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作者： John B,Connolly ^[1] ; John D,Mumford ^[2] ; Silke,Fuchs ^[3] ; Geoff,Turner ^[3] ; Camilla,Beech ^[4] ; Ace R,North ^[5] ; Austin,Burt ^[3]

作者单位： Department of Life Sciences, Imperial College London, London, UK. john.connolly12@imperial.ac.uk. ^[1] Centre for Environmental Policy, Imperial College London, London, UK. ^[2] Department of Life Sciences, Imperial College London, London, UK. ^[3] Cambea Consulting Ltd, Reading, UK. ^[4] Department of Zoology, University of Oxford, Oxford, UK. ^[5]

关键词 Anopheles Environmental risk assessment (ERA)Field release Gene drive Malaria Pathways to harm Population suppression gene drive Problem formulation Transgenic Vector control

主题词非洲, 西部(Africa, Western);动物(Animals);动物, 基因修饰(Animals, Genetically Modified);按蚊属(Anopheles);疟疾(Malaria);灭蚊(Mosquito Control);转基因(Transgenes)

DOI 10.1186/s12936-021-03674-6

PMID 33781254

发布时间 2024-12-07

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