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VRK2 is involved in the innate antiviral response by promoting mitostress-induced mtDNA release.

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第一作者： Wen-Rui,He

第一单位： Department of Infectious Diseases, Frontier Science Center for Immunology and Metabolism, Medical Research Institute, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China.;Research Unit of Innate Immune and Inflammatory Diseases, Chinese Academy of Medical Sciences, Wuhan, China.

作者： Wen-Rui,He ^[1] ; Li-Bo,Cao ^[1] ; Yu-Lin,Yang ^[1] ; Duo,Hua ^[1] ; Ming-Ming,Hu ^[2] ; Hong-Bing,Shu ^[3]

作者单位： Department of Infectious Diseases, Frontier Science Center for Immunology and Metabolism, Medical Research Institute, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China.;Research Unit of Innate Immune and Inflammatory Diseases, Chinese Academy of Medical Sciences, Wuhan, China. ^[1] Department of Infectious Diseases, Frontier Science Center for Immunology and Metabolism, Medical Research Institute, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China. mmhu@whu.edu.cn.;Research Unit of Innate Immune and Inflammatory Diseases, Chinese Academy of Medical Sciences, Wuhan, China. mmhu@whu.edu.cn. ^[2] Department of Infectious Diseases, Frontier Science Center for Immunology and Metabolism, Medical Research Institute, Zhongnan Hospital of Wuhan University, Wuhan University, Wuhan, China. shuh@whu.edu.cn.;Research Unit of Innate Immune and Inflammatory Diseases, Chinese Academy of Medical Sciences, Wuhan, China. shuh@whu.edu.cn. ^[3]

关键词 Mita/Sting cGAS innate immune response mitochondrial DNA mitostress