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Antitumor efficacy of a neoantigen cancer vaccine delivered by electroporation is influenced by microbiota composition.

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第一作者： Lucia,Lione

第一单位： Cancer Immunology, Takis, Rome, Italy.;Università Magna Grecia, Catanzaro, Italy.

作者： Lucia,Lione ^[1] ; Erika,Salvatori ^[2] ; Adriana,Petrazzuolo ^[3] ; Alice,Massacci ^[4] ; Roberta,Maggio ^[4] ; Antonella,Confroti ^[2] ; Mirco,Compagnone ^[5] ; Luigi,Aurisicchio ^[6] ; Gennaro,Ciliberto ^[7] ; Fabio,Palombo ^[8]

作者单位： Cancer Immunology, Takis, Rome, Italy.;Università Magna Grecia, Catanzaro, Italy. ^[1] Evvivax, Rome, Italy. ^[2] Cancer Immunology, Takis, Rome, Italy.;Equipe Labellisée Par La Ligue Contre Le Cancer, Université De Paris, Sorbonne Université, INSERM U1138, Centre De Recherche Des Cordeliers, Paris, France.;Metabolomics and Cell Biology Platforms, Gustave Roussy Cancer Campus, Villejuif, France.;Biogem, Ariano Irpino, Italy. ^[3] Cancer Immunology, Takis, Rome, Italy. ^[4] Université Paris Saclay, Faculty of Medicine Kremlin Bicêtre, France.;Université Paris Saclay, Faculty of Medicine Kremlin Bicêtre, France. ^[5] Cancer Immunology, Takis, Rome, Italy.;Evvivax, Rome, Italy.;Biogem, Ariano Irpino, Italy.;Université Paris Saclay, Faculty of Medicine Kremlin Bicêtre, France. ^[6] Cancer immunology, Neomatrix, Rome, Italy.;Scientific Directorate, IRCCS Regina Elena National Cancer Institute, Rome, Italy. ^[7] Cancer Immunology, Takis, Rome, Italy.;Université Paris Saclay, Faculty of Medicine Kremlin Bicêtre, France. ^[8]

关键词 Microbiota T cells neoantigens vaccine

医学主题词抗原, 肿瘤(Antigens, Neoplasm);癌症疫苗(Cancer Vaccines);电穿孔(Electroporation);免疫疗法(Immunotherapy);肿瘤(Neoplasms)

DOI 10.1080/2162402X.2021.1898832

PMID 33796408

发布时间 2023-11-11

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