Automated evaluation of tumor spheroid behavior in 3D culture using deep learning-based recognition.

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第一作者： Zaozao,Chen

第一单位： State Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing, Jiangsu, 210096, China; Institute of Biomaterials and Medical Devices, Southeast University, Suzhou, Jiangsu, 215163, China.

作者： Zaozao,Chen ^[1] ; Ning,Ma ^[2] ; Xiaowei,Sun ^[3] ; Qiwei,Li ^[4] ; Yi,Zeng ^[4] ; Fei,Chen ^[3] ; Shiqi,Sun ^[3] ; Jun,Xu ^[3] ; Jing,Zhang ^[3] ; Huan,Ye ^[3] ; Jianjun,Ge ^[3] ; Zheng,Zhang ^[4] ; Xingran,Cui ^[4] ; Kam,Leong ^[5] ; Yang,Chen ^[6] ; Zhongze,Gu ^[7]

作者单位： State Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing, Jiangsu, 210096, China; Institute of Biomaterials and Medical Devices, Southeast University, Suzhou, Jiangsu, 215163, China. ^[1] School of Computer Science and Engineering, Southeast University, Nanjing, Jiangsu, 210096, China. ^[2] Institute of Biomaterials and Medical Devices, Southeast University, Suzhou, Jiangsu, 215163, China. ^[3] State Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing, Jiangsu, 210096, China. ^[4] Department of Biomedical Engineering, Columbia University, New York, NY, 10032, USA. ^[5] School of Computer Science and Engineering, Southeast University, Nanjing, Jiangsu, 210096, China. Electronic address: chenyang.list@seu.edu.cn. ^[6] State Key Laboratory of Bioelectronics, School of Biological Science and Medical Engineering, Southeast University, Nanjing, Jiangsu, 210096, China; Institute of Biomaterials and Medical Devices, Southeast University, Suzhou, Jiangsu, 215163, China. Electronic address: gu@seu.edu.cn. ^[7]

关键词 3D culture Cancer invasiveness Deep learning Microphysiological System

主题词细胞系, 肿瘤(Cell Line, Tumor);细胞存活(Cell Survival);药物评价, 临床前(Drug Evaluation, Preclinical);球形体, 细胞(Spheroids, Cellular)

DOI 10.1016/j.biomaterials.2021.120770

PMID 33798957

发布时间 2021-05-27

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准确一般字义偏差语意偏离译文作用小提交