Shifting the Gears of Metabolic Plasticity to Drive Cell State Transitions in Cancer.

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作者： Zhengwei,Wu ^[1] ; Yi Fei,Lee ^[2] ; Xun Hui,Yeo ^[1] ; Ser Yue,Loo ^[3] ; Wai Leong,Tam ^[4]

作者单位： Cancer Science Institute of Singapore, National University of Singapore, 14 Medical Drive, Singapore 117599, Singapore.;Genome Institute of Singapore, 60 Biopolis Street, Singapore 138672, Singapore. ^[1] Genome Institute of Singapore, 60 Biopolis Street, Singapore 138672, Singapore.;School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, Singapore 637551, Singapore. ^[2] Genome Institute of Singapore, 60 Biopolis Street, Singapore 138672, Singapore. ^[3] Cancer Science Institute of Singapore, National University of Singapore, 14 Medical Drive, Singapore 117599, Singapore.;Genome Institute of Singapore, 60 Biopolis Street, Singapore 138672, Singapore.;School of Biological Sciences, Nanyang Technological University, 60 Nanyang Drive, Singapore 637551, Singapore.;Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, 8 Medical Drive, Singapore 117597, Singapore. ^[4]

关键词 cancer stem cells cell state transition cellular plasticity epithelial–mesenchymal transition phenotype switching therapy resistance

DOI 10.3390/cancers13061316

PMID 33804114

发布时间 2024-08-08

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